ArticleGMS hygiene and infection control2026
Virucidal efficacy of a UV-C disinfection system for semi-critical medical devices according to EN 14476.
Article in GMS hygiene and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Purpose: Semi-critical medical devices, such as flexible endoscopes in otorhinolaryngology (ORL), require high-level disinfection due to their contact with mucous membranes. UV-C systems offer a rapid, non-toxic alternative to traditional reprocessing. This study evaluates the virucidal efficacy of the D60 UV-C disinfection system according to EN 14476 standards. Materials and methods: Standardized tests were performed using frosted glass and thermoplastic elastomer (TPE) carriers inoculated with four indicator viruses: murine norovirus (MNV), poliovirus type 1, adenovirus type 5, and simian virus 777 (SV40). After drying, carriers underwent a 60 second UV-C cycle in the D60 system. Viral recovery and titration followed EN 14476 protocols, with infectivity measured by TCID Results: All viruses showed significant reductions following UV-C treatment. Residual titers fell below the detection limit (3.2 lg TCID Conclusion: The D60 system achieved broad-spectrum virucidal efficacy within one minute, meeting EN 14476 requirements. These findings support its use for safe, rapid reprocessing of semi-critical devices in high-turnover clinical settings, with potential to improve infection control and workflow efficiency.
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