ArticleFrontiers in cardiovascular medicine2026
Psychosocial outcome of COVID-19 patients requiring ventilation after ECMO versus long-term mechanical ventilation.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Severe COVID-19 frequently necessitates prolonged intensive care treatment, including long-term mechanical ventilation (MV) and extracorporeal membrane oxygenation (ECMO). While survival outcomes of these modalities have been extensively studied, data on long-term psychological sequelae remain limited. This study compared psychosocial outcomes in COVID-19 ICU survivors treated with ECMO vs. prolonged MV alone. Materials and methods: In this exploratory single-centre study combined retrospective clinical data with prospective long-term psychosocial follow-up, 150 adult patients with severe COVID-19 treated between March 2020 and December 2021 were included (ECMO: Results: ECMO patients were significantly younger (mean 53.8 vs. 66.0 years; Conclusion: Survivors of severe COVID-19 requiring either ECMO or prolonged mechanical ventilation exhibit a substantial long-term psychological burden. Distinct psychosocial profiles were observed between treatment modalities, with higher attachment-related anxiety among MV survivors and numerically greater depressive and trauma-related symptoms among ECMO survivors. These findings highlight the importance of systematic post-ICU psychological screening and the integration of psychosocial outcomes into long-term critical care follow-up.
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