Evidence map›Paper›PMID 41815763›Full record

ArticleJCPP advances2026

Targeting intolerance of uncertainty in young children diagnosed with autism: A randomized controlled trial of a parent-mediated group intervention.

Claudia S Y Ong, Jacqui Rodgers, Matthew N Cooper, Zac Dempsey, Rebecca Eaton, Katia Haines, Rebecca Kuzminski, Iliana Magiati, Murray T Maybery, Mirko Uljarević and 3 more

Abstract read
In one paragraph

Article in JCPP advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Claudia S Y OngThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0001-8980-642X
Jacqui RodgersPopulation Health Sciences Institute Newcastle University Newcastle UK.ORCID https://orcid.org/0000-0002-1759-316X
Matthew N CooperThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0003-1139-3682
Zac DempseyThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0009-0006-5698-7803
Rebecca EatonThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.
Katia HainesThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.
Rebecca KuzminskiThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0002-9755-3407
Iliana MagiatiSchool of Psychological Science The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0001-7261-7366
Murray T MayberySchool of Psychological Science The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0002-3760-1382
Mirko UljarevićDepartment of Psychiatry and Behavioural Sciences Stanford University Stanford California USA.ORCID https://orcid.org/0000-0002-8414-4209
John WrayWA Department of Health Child Development Service Perth Western Australia Australia.ORCID https://orcid.org/0000-0001-7549-6678
Andrew J O WhitehouseThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0001-8722-1575
Gail A AlvaresThe Kids Research Institute Australia The University of Western Australia Perth Western Australia Australia.ORCID https://orcid.org/0000-0003-3351-5919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Young children diagnosed with autism experience high rates of co-occurring anxiety, with uncertainty-related concerns commonly reported. This randomized controlled trial investigated an 8-week parent-mediated group anxiety intervention, "Coping with Uncertainty in Everyday Situations" (CUES-Junior©). Methods: Parents of 4-7-year-old children diagnosed with autism and experiencing uncertainty-related anxiety were recruited. The primary outcome was change from baseline in blinded assessor ratings of child responses to uncertainty and impact on family, measured post-intervention and 2-month follow-up. Secondary outcomes were parent-reported child anxiety and intolerance of uncertainty (IU), parental IU and mental health, parenting sense of competence, along with intervention feasibility and acceptability. Results: Sixty-four children were randomized to CUES-Junior© ( Conclusions: CUES-Junior© had an immediate treatment effect on child responses to uncertain situations and impact on families, with maintained improvements observed at follow-up. This novel mechanism-targeted and autism-informed program holds promise for addressing early uncertainty-related anxiety in young children diagnosed with autism.

Indexed as

anxietyautism spectrum disorderscognitive therapyparent‐child relationshipsRCT design

Identifiers

PMID41815763
PMCPMC12973137

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.