ArticleJournal of orthopaedic case reports2026
Use of Autologous Platelet-rich Plasma as a Biological Adjunct in Distal Humerus Non-union: A Case Report.
Article in Journal of orthopaedic case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Introduction: Distal humerus fractures are uncommon injuries with a known risk of non-union despite surgical fixation. Revision surgery with bone grafting remains standard, but some patients may decline reoperation or may be unfit for surgery. Platelet-rich plasma (PRP), an autologous biological product rich in growth factors, may enhance healing in selected cases. Case Report: A woman in her 30s developed an aseptic non-union of the distal humerus 6 months after internal fixation for a complex fracture. As she declined revision surgery, she was managed non-surgically with autologous PRP injections. Seven injections were administered over 4 consecutive days using anatomical landmarks. Pain progressively reduced, function improved, and radiographs demonstrated bridging callus and cortical continuity by 6 months. Conclusion: In stable fixation with aseptic atrophic non-union, PRP may act as a minimally invasive biological adjunct to support bone healing. Careful patient selection and monitoring are essential for success.
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