Evidence map›Paper›PMID 41815646›Full record

ArticleJournal of orthopaedic case reports2026

Bilateral Clubfoot in Nail-Patella Syndrome: A Rare Syndromic Case Successfully Treated with the Ponseti Method.

Burhanuddin F Chhatriwala, Binoti Sheth, Sri Hari Ram V S, Suyog Wagh, Aibin B Micheal, Shubham Atal

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Article in Journal of orthopaedic case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Burhanuddin F ChhatriwalaDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Binoti ShethDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Sri Hari Ram V SDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Suyog WaghDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Aibin B MichealDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Shubham AtalDepartment of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Nail-patella syndrome (NPS) is a rare autosomal dominant disorder characterized by nail dysplasia, hypoplastic or absent patellae, elbow anomalies, and iliac horns. Its association with congenital talipes equinovarus, or clubfoot, is extremely uncommon and rarely documented. Case Report: We describe a 1.5-year-old male child, born of a 2° consanguineous marriage, who presented with bilateral clubfoot and complete absence of fingernails. Great toenails were absent bilaterally, whereas the remaining toenails were preserved. The patellae were non-palpable clinically, and ultrasound confirmed the absence of ossification centers bilaterally. Radiographs revealed bilateral iliac horns. Ponseti casting was initiated at 2 months of age, and full correction was achieved after five casts, followed by bilateral percutaneous Achilles tenotomy. At 6-month follow-up, the patient exhibited plantigrade, pain-free feet with good dorsiflexion and no recurrence. Conclusion: NPS can occasionally be associated with flexible clubfoot, which may respond well to conservative management. The Ponseti method, when initiated early, remains an effective option in such rare syndromic presentations.

Indexed as

clubfootcongenital talipes equinovarusLMX1B mutationNail-patella syndromePonseti methodsyndromic clubfoot

Identifiers

PMID41815646
PMCPMC12973032

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