ArticleCureus2026
Epidemiological Analysis and Susceptibility Profile of Pathogens Isolated in Blood Cultures From Hospital Angeles Lindavista in Mexico City.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Background Bloodstream infections contribute to morbidity and mortality. A wide variety of microorganisms can be identified and recovered from these infections, and blood culture is the primary method for detecting them and determining their antimicrobial susceptibility. This helps clinicians confirm the efficacy of the initial empiric therapy or select an appropriate alternative based on the susceptibility of the isolated microorganism, thereby reducing the risks associated with antimicrobial misuse. We aimed to describe and analyze the bacteria isolated in blood culture samples, their antimicrobial resistance at Hospital Angeles Lindavista, and their association with demographic and clinical characteristics; to provide tools for the effective antimicrobial treatment of bacteremia; and to monitor the evolution of microbial resistance in this institution. Methods A retrospective observational study was conducted at Hospital Angeles Lindavista, including all patients with suspected sepsis, as determined by the physician's judgement, who had at least one blood sample collected from January 2024 to December 2024. Variables examined included age, gender, clinical service, comorbidities, risk factors, diagnoses, detected pathogens, and antibiogram. The relationship between a specific bacterium and an affected organ system was analyzed using a chi-square test, followed by residual analysis. To explore potential associations between clinical variables, regression models were used. Finally, to verify the stability of the results, we performed a sensitivity analysis using only complete cases and compared these findings to those from the entire dataset. The statistical analysis was conducted using R version 4.4.1 (2024-06-14 ucrt) (R Foundation for Statistical Computing, Vienna, Austria) in RStudio (Posit Software, Boston, MA). Results We identified an adult population with a median age of 49 years and a predominance of men. The median hospital stay was eight days; hospitalization was the most common service, and the gastrointestinal system was most affected. Regarding risk factors, 31 patients (16%) had type 2 diabetes mellitus, and sepsis was the most frequent diagnosis (n = 18, 9%).
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