Evidence map›Paper›PMID 41815583›Full record

ArticleCureus2026

Antibiotic Prescribing Patterns in Hospitalized Pediatric Patients With Clinically Suspected Enteric Fever: A Descriptive Study.

Gulam Abdul Kadir Khan, Muhammad Arslan Siddiqui, Dheeraj Bansal, Jagan Nadipelly, Hardat Persaud

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Gulam Abdul Kadir KhanMedicine, Texila American University, Georgetown, GUY.
Muhammad Arslan SiddiquiMedicine, Texila American University, Georgetown, GUY.
Dheeraj BansalPublic Health Sciences, Texila American University, Georgetown, GUY.
Jagan NadipellyPharmacology, Texila American University, Georgetown, GUY.
Hardat PersaudPediatrics, Woodlands Hospital, Georgetown, GUY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnteric fever remains an important cause of morbidity among children in developing regions and is frequently managed with empirical antimicrobial therapy. In the setting of evolving antimicrobial resistance and diagnostic limitations, describing real-world antibiotic prescribing practices in pediatric patients is essential. This study aimed to describe antibiotic prescribing patterns among hospitalized pediatric patients with clinically suspected enteric fever and to explore their distribution across clinical and laboratory parameters.

methodsA hospital-based retrospective observational study was conducted among 100 hospitalized pediatric patients (>2 years of age) clinically diagnosed with enteric fever. Demographic details, clinical features, vaccination status, laboratory parameters (hemoglobin, total leukocyte count, erythrocyte sedimentation rate, platelet count, C-reactive protein, and Widal test results), and treatment details were extracted from medical records. Antibiotic utilization patterns involving injectable ceftriaxone, injectable ofloxacin, injectable amikacin, and oral doxycycline were analyzed using descriptive statistics. Associations between antibiotic use and selected clinical and laboratory variables were explored using the chi-square test, with a p-value ≤0.05 considered statistically significant.

resultsThe mean age of patients was 6.03±3.08 years, with a near-equal gender distribution. Fever was the most common presenting symptom (90%), followed by vomiting (45%) and abdominal pain (23%). Laboratory evaluation revealed mild anemia and elevated inflammatory markers in a proportion of patients. Injectable ceftriaxone was the most frequently prescribed antibiotic (83%), followed by oral doxycycline (27%), injectable ofloxacin (26%), and injectable amikacin (11%). Variations in antibiotic use were observed across different clinical features, laboratory parameters, and treatment intensity. Age did not show a statistically significant association with antibiotic selection.

conclusionThis study describes prevailing antibiotic prescribing patterns among hospitalized pediatric patients with clinically suspected enteric fever. Injectable ceftriaxone was the most commonly used empirical antibiotic, while other agents were prescribed selectively. The findings highlight existing prescribing trends in inpatient pediatric care and underscore the need for improved microbiological confirmation to better inform antibiotic selection in enteric fever.

Indexed as

antibiotic prescribing patternsceftriaxoneempirical antibiotic therapyhospitalized childrenpediatric enteric fever

Identifiers

PMID41815583
PMCPMC12973113

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