Evidence map›Paper›PMID 41815533›Full record

ArticleExposure and health2026

Multichemical Exposure Assessment Using Silicone Wristbands in Central American Adolescents.

Yirong Yuan, Samantha M Hall, Juan José Amador Velázquez, Damaris López Pilarte, Selene Vences Brown, Magaly Amador Sánchez, Juan Amador Sánchez, Birgit Claus Henn, Madeleine K Scammell, David J Friedman and 2 more

Abstract read
In one paragraph

Article in Exposure and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yirong YuanDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.ORCID 0009-0001-3299-4922
Samantha M HallDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.
Juan José Amador VelázquezCentro Médico del Pacífico (CENMED), Masaya, Nicaragua.
Damaris López PilarteCentro Médico del Pacífico (CENMED), Masaya, Nicaragua.
Selene Vences BrownDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.
Magaly Amador SánchezCentro Médico del Pacífico (CENMED), Masaya, Nicaragua.
Juan Amador SánchezCentro Médico del Pacífico (CENMED), Masaya, Nicaragua.
Birgit Claus HennDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.
Madeleine K ScammellDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.
David J FriedmanDivision of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA USA.
Daniel R BrooksDepartment of Epidemiology, Boston University School of Public Health, Boston, MA USA.
Jessica H LeiblerDepartment of Environmental Health, Boston University School of Public Health, 715 Albany St, Boston, MA 02118 USA.ORCID 0000-0002-0605-0928

Funding

Environmental Epidemiology in Community SettingsT32ES014562 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Birgit Gunhild Claus Henn · 2006 to 2026
$7.7M
The NINOS cohort: Children's Kidney Health in a High-Risk Region for CKDuR01ES031606 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LEIBLER, JESSICA H · 2021 to 2025
$3.0M
Metals, the Microbiome, and Kidney Health Among Adolescents in Central AmericaF31ES036454 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HALL, SAMANTHA · 2024 to 2025
$99k
NIEHS NIH HHS F31 ES036454NIEHS NIH HHS R01 ES031606NIEHS NIH HHS T32 ES014562
6 · The paper itself

Abstract

Chemical exposures are poorly characterized in Central America, where chronic kidney disease of uncertain etiology (CKDu) is a leading cause of death. Most research evaluates occupational exposures in adults, yet early-life exposures remain understudied. We used silicone wristband passive samplers to characterize exposure to over 1,500 chemicals among Nicaraguan adolescents (

Indexed as

Central AmericaChemical exposureChemical mixtureCKDuMesoamerican nephropathySilicone wristband

Identifiers

PMID41815533
PMCPMC12971789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.