ArticleInternational journal of cardiology. Cardiovascular risk and prevention2026
Evaluating the incremental value of an expanded cardiovascular health score for the prevalence of abdominal aortic calcification among middle-aged and elderly individuals.
Article in International journal of cardiology. Cardiovascular risk and prevention, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Beyond AUC: Questioning the clinical interpretation of "superior" discrimination in cardiovascular health scores.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
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3 authors.
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Abstract
Objective: This study aimed to investigate the relationship between three cardiovascular health scores-Life's Simple 7 (LS7), Life's Essential 8 (LE8), and Life's Crucial 9 (LC9)-and the prevalence of abdominal aortic calcification (AAC) and severe AAC among middle-aged and elderly individuals using data from NHANES 2013-2014. Methods: We analyzed data from 2484 adults aged 40 years and older with dual-energy X-ray absorptiometry (DXA) scans. Logistic regression models evaluated associations between each cardiovascular health score and AAC prevalence. The discriminatory ability of each score was compared using receiver operating characteristic (ROC) analysis, with area under the curve (AUC) values, net reclassification improvement (NRI), and integrated discrimination improvement (IDI). Results: In fully adjusted models, low LS7 scores were significantly associated with higher odds of AAC (OR = 2.16 [1.33-3.50]) and severe AAC (OR = 3.21 [1.45-7.13]), compared to high LS7 scores. While similar associations were observed for LE8 and LC9, LS7 demonstrated the strongest ability to differentiate individuals with and without AAC, as reflected by its higher AUC values. Adding LS7 to fully adjusted models improved model discrimination for both AAC and severe AAC, with significant NRI and IDI values. Conclusion: These findings suggest that lower cardiovascular health scores are associated with increased AAC and severe AAC prevalence, with LS7 demonstrating the highest discriminatory ability.
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