Evidence map›Paper›PMID 41815307›Full record

ArticleStroke (Hoboken, N.J.)2026

Endovascular Treatment in Subtypes of Posterior Large Vessel Occlusion: A Pooled Analysis From 2 Registries.

Li Wei, Yusi Fu, KaiLai Huang, Liying Pan, Rong Chen, Zhizhong Yan, Weidong Hu, Zhiliang Li, Hongmei Xu, Wentong Ling and 28 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Li WeiKey Laboratory of Emergency and Trauma of Ministry of Education, Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, China (L.W., K.H., R.C., Y.D., Z.Z.).ORCID https://orcid.org/0000-0001-7247-2478
Yusi FuDepartment of Neurology, The First Affiliated Hospital of Jinan University, Guangzhou, China (Y.F.).
KaiLai HuangKey Laboratory of Emergency and Trauma of Ministry of Education, Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, China (L.W., K.H., R.C., Y.D., Z.Z.).ORCID https://orcid.org/0009-0001-7904-414X
Liying PanDepartment of Neurology, Longyan First Affiliated Hospital of Fujian Medical University, China (L.P., C.Z.).
Rong ChenKey Laboratory of Emergency and Trauma of Ministry of Education, Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, China (L.W., K.H., R.C., Y.D., Z.Z.).
Zhizhong YanDepartment of Neurosurgery, The 904th Hospital of The People's Liberation Army, Wuxi, China (Z.Y.).ORCID https://orcid.org/0000-0001-5237-1880
Weidong HuDepartment of Neurology, Dongguan People's Hospital, China (W.H.).
Zhiliang LiDepartment of Neurology, Huazhou People's Hospital, China (Z.L.).
Hongmei XuDepartment of Neurology, No. 903 Hospital of PLA Joint Logistic Force, Hangzhou, China (H.X.).
Wentong LingDepartment of Neurology, Zhongshan City People's Hospital, China (W.L., Q.L.).
Qingyun LeiDepartment of Neurology, Zhongshan City People's Hospital, China (W.L., Q.L.).
Huajian LiDepartment of Neurology, Hainan Third People's Hospital, SanYa, China (H.L.).
Lue ChenDepartment of Neurology, Shunde Hospital of Southern Medical University, China (Lue Chen).
Fan ZhangDepartment of Neurology, The Affiliated Ganzhou Hospital of Nanchang University, China (F.Z.).ORCID https://orcid.org/0000-0002-4569-1891
Shizhang LiDepartment of Neurology, The First People's Hospital of Yulin, China (S.L.).
Chong ZhengDepartment of Neurology, Longyan First Affiliated Hospital of Fujian Medical University, China (L.P., C.Z.).ORCID https://orcid.org/0000-0001-8040-0511
Jianheng WuDepartment of Neurology, Zhongshan Hospital of Traditional Chinese Medicine, China (J.W.).
Min ZhangDepartment of Neurology, Chinese Medical Hospital of Maoming, China (M.Z.).
Delang LiuDepartment of Neurology, Guangdong Province Hospital of Chinese Medicine, Hainan Hospital, Haikou, China (D.L.).
Jie PuDepartment of Neurology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China (J.P.).
Guoyi PengDepartment of Neurosurgery, Shantou Central Hospital, China (G.P.).
Guang ZhangDepartment of Neurosurgery, The First Affiliated of Harbin Medical University, China (G.Z.).ORCID https://orcid.org/0000-0002-9428-2568
Yunyun LiDepartment of Neurology, Maanshan People's Hospital, China (Y.L.).
Luming ChenDepartment of Neurology, The 928th Hospital of People's Liberation Army Joint Logistic Support Force, Haikou, China (Luming Chen).
Geng LiaoDepartment of Neurology, Maoming People's Hospital, China (G.).
Lei YuDepartment of Neurosurgery, Danzhou People's Hospital, China (L.Y.).
Fei ChenDepartment of Neurology, Qionghai People's Hospital, China (F.C.).
Xi LiDepartment of Neurology, The General Hospital of Western Theater Command, Chengdu, China (X.L.).
Zhangbao GuoDepartment of Neurology, Wuhan No 1 Hospital, China (Z.G.).
Mingchao LiDepartment of Neurology, Huai'an First People's Hospital, China (M.L.).
Zheng DaiDepartment of Neurology, Wuxi People's Hospital, China (Z.D.).ORCID https://orcid.org/0000-0003-2267-851X
Yonggang HaoDepartment of Neurology, The Fourth Affiliated Hospital of Soochow University, Suzhou, China (Y.H.).
Yangyang DuanKey Laboratory of Emergency and Trauma of Ministry of Education, Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, China (L.W., K.H., R.C., Y.D., Z.Z.).
Zhongming QiuDepartment of Neurology, The 903th Hospital of People's Liberation Army, Hangzhou, China (Z.Q.).ORCID https://orcid.org/0000-0002-1622-9526
Chang LiuDepartment of Neurology, Chongqing Medical University, China (C.L.).ORCID https://orcid.org/0000-0002-9923-2324
Tingyu YiDepartment of Neurology, Zhangzhou Affiliated Hospital of Fujian Medical University, China (T.Y.).ORCID https://orcid.org/0000-0003-3110-5844
Mohamed F DoheimDepartment of Neurology, Stroke Institute, University of Pittsburgh Medical Center, PA (M.F.D.).ORCID https://orcid.org/0000-0001-8279-5078
Zhenqiang ZhaoKey Laboratory of Emergency and Trauma of Ministry of Education, Department of Neurology, The First Affiliated Hospital of Hainan Medical University, Haikou, China (L.W., K.H., R.C., Y.D., Z.Z.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent evidence on differential outcomes of endovascular therapy for the different pathological subtypes of vertebrobasilar artery occlusion is still limited. The study aimed to compare characteristics and clinical outcomes among distinct pathological subtypes of vertebrobasilar artery occlusion undergoing endovascular therapy.

methodsThis was a posthoc pooled analysis of 1320 patients from the BASILAR (Endovascular Treatment for Acute Basilar Artery Occlusion Study; 2014-2019) and the PERSIST (Posterior Circulation Ischemic Stroke Registries; 2015-2018) registries. This analysis included adults (≥18 years) with moderate to severe vertebrobasilar artery occlusion who underwent endovascular therapy within 24 hours of their last known well. Patients were stratified by stroke mechanism: group 1 (embolism without vertebral stenosis), group 2 (tandem embolism from vertebral stenosis/occlusion), and group 3 (in situ atherosclerotic thrombosis). Baseline characteristics, procedural details, and clinical outcomes were compared across these 3 groups. The primary outcome was a favorable functional outcome, defined as a modified Rankin Scale score of 0 to 3 at 90 days. Baseline characteristics, procedural details, and clinical outcomes were compared across these 3 groups. Because the primary independent variable was categorical with no single referent category, all comparisons among the 3 groups were conducted as exploratory analyses.

resultsA total of 1067 patients were included (group 1, n=257 [24.08%]; group 2, n=176 [16.49%]; group 3, n=634 [59.42%]). The overall successful recanalization rate was 84.72% (904/1067), and the favorable functional outcome (90-day modified Rankin Scale score of 0-3) rate was 33.40% (275/1063). The procedure time in group 1 was significantly shorter than that in groups 2 and 3 (median time, 90 versus 135 and 110 minutes,

conclusionsThe outcome of endovascular therapy for vertebrobasilar artery occlusion may vary based on the stroke mechanism; patients with embolism without vertebral artery steno-occlusion may achieve excellent outcomes compared with other causes. REGISTRATION: URL: http://www.chictr.org.cn; Unique identifier: CTR1800014759 and CTR2000033211.

Indexed as

basilar arteryembolismischemic strokethrombosisvertebral artery

Identifiers

PMID41815307
PMCPMC12959435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.