ArticleSe pu = Chinese journal of chromatography2026
[Preparation of magnetic bifunctional materials for exosome capture from serum and phosphopeptide enrichment].
Article in Se pu = Chinese journal of chromatography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
As a clinical sample， serum is widely used in disease research due to the minimally invasive nature of its collection and easy accessibility. Exosomes in serum not only carry various bioactive substances such as proteins and nucleic acids but also participate in intercellular communication， which is closely associated with the development of multiple diseases. As one of the most critical post-translational modifications， protein phosphorylation dynamically regulates cellular signaling networks and participates in disease pathogenesis. However， due to the low abundance of exosomes in serum and the fact that phosphoproteins constitute only 1%-2% of the total proteome， direct analysis of exosomal phosphoproteins from serum faces significant challenges. The specific expression of phosphoproteins in exosomes provides novel perspectives for disease diagnosis. In this study， magnetic bifunctional nanoparticles （MagphTi
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