Trial reportPhysiological reports2026
Similarities and differences in carotid artery, hemodynamic, and autonomic reactivity induced by mental stress or cold in adults: A randomized crossover study.
Trial report in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
6 authors.
Funding
Abstract
The cold pressor test (CPT) is used to investigate cardiovascular and autonomic responses, while the Stroop color-word test (Stroop) is also used for this purpose, although its vascular effects require further understanding. This randomized crossover study compared vascular, hemodynamic, and autonomic responses induced by cold and mental stress. Twenty participants (10 females; 25.7 ± 5.2 years) underwent the Stroop and CPT. Carotid artery reactivity (CAR) was evaluated using ultrasound. Arterial pressure (AP), heart rate (HR), and R-R intervals (RRi) were continuously recorded. RRi were used to infer autonomic modulation through HR variability. Parametric data are reported as mean ± SD and non-parametric data as median (p25-p75). CAR magnitude did not differ between tests (Stroop: 2.8 ± 3.6; CPT: 4.1 ± 4.2%; p = 0.236), although Stroop elicited a shorter time to peak (66.5 ± 56.5 vs. 99.5 ± 35.1 s; p = 0.020). CPT induced a greater rise in diastolic AP (Stroop: 8.5 (6.2-10.0); CPT: 13.0 (6.2-23.5) mmHg; p = 0.009) and mean AP (Stroop: 8.4 ± 4.2; CPT: 13.5 ± 8.5 mmHg; p = 0.023). Stroop produced a larger HR increase (20.5 (10.2-27.7) vs. 11.0 (5.2-14.7) bpm; p = 0.013) and larger decrease in parasympathetic modulation (RMSSD - Stroop: -21.3 (-39.6 to -10.0); CPT: -12.8 (-22.8 to 0.95) ms; p = 0.026; HF - Stroop: -2.3 ± 1.3; CPT: -0.61 ± 0.74 Ln ms
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