Evidence map›Paper›PMID 41814680›Full record

ArticleAnnals of medicine2026

Cross-cultural validation and reliability of the Leicester Cough Questionnaire in a Danish population.

Frederik Foldager, Christine Krogsgaard Schrøder, Tatiana Jensen, Line Gangelhof Lauritsen, Janne Hastrup Jensen, Linette Marie Kofod, Jeanett Guldager Olsen, Benedicte Mechlenburg, Arietta Spinou, William Poncin and 1 more

Abstract readValidation Study
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Frederik FoldagerDepartment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-8675-9653
Christine Krogsgaard SchrøderDepartment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-6022-256X
Tatiana JensenDepartment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.
Line Gangelhof LauritsenDepartment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.
Janne Hastrup JensenDepartment of Physical Therapy and Occupational, Aarhus University Hospital, Aarhus N, Denmark.
Linette Marie KofodDepartment of Physical and Occupational Therapy, Copenhagen University Hospital, Hvidovre, Copenhagen, Denmark.
Jeanett Guldager OlsenHvidovre Municipality, Capital Region, Copenhagen, Denmark.
Benedicte MechlenburgDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Arietta SpinouPopulation Health Sciences, King's College London, London, United Kingdom.ORCID 0000-0002-3442-4739
William PoncinPole of Pulmonology, ENT and Dermatology (LUNS), Institute of Experimental and Clinical Research (IREC), Université Catholique de Louvain (UCLouvain), Brussels, Belgium.ORCID 0000-0002-7686-2294
Inger MechlenburgDepartment of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-5432-8691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic cough markedly impairs health-related quality of life (HRQoL). The Leicester Cough Questionnaire (LCQ) is widely used to assess cough burden across physical, psychological, and social domains; however, no validated Danish version is available. MATERIALS AND

methodsThe LCQ was translated and culturally adapted into Danish in accordance with COSMIN guidelines and was approved by the original developers. Forty-two clinically stable patients with chronic cough (mean age 70.8 years; 67% male) completed baseline and retest questionnaires at a median of 28 days (IQR 21-42). Internal consistency was examined with Cronbach's alpha. Test-retest reliability was assessed using intraclass correlation coefficients (ICC), standard error of measurement (SEM), and minimal detectable change (MDC).

resultsThe LCQ-DK demonstrated excellent internal consistency (Cronbach's alpha = 0.96 total; 0.84-0.92 domains). Test-retest reliability was high (ICC = 0.90, 95% CI: 0.79-0.95 total; 0.86-0.89 domains). SEM was 1.14 points (8%) and MDC 3.16 points (23%) for the total score. No floor or ceiling effects were seen for the total score, though ceiling effects up to 12% occurred within domains.

conclusionThe LCQ-DK demonstrates high reliability following cross-cultural adaptation and supports group-level assessment of HRQoL in Danish-speaking patients with chronic cough for clinical and research use.

Indexed as

Chronic CoughCoughQuality of LifeAgedAged, 80 and overCross-Cultural ComparisonDenmarkFemaleHumansMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesTranslationschronic coughcross-cultural adaptationinternal consistencyLeicester Cough Questionnairereliabilitytranslation

Identifiers

PMID41814680
PMCPMC12983802

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.