Evidence map›Paper›PMID 41814369›Full record

ArticleItalian journal of pediatrics2026

Neuropsychological profile and clinical benefits of multimodal interventions in a child with ADHD, Generalized Anxiety Disorder, and Social (Pragmatic) Communication Disorder within the context of intellectual giftedness: a case report.

Andrea Battisti, Cristiana Varuzza, Giulia Brunozzi, Giulia Lazzaro, Pietro De Rossi, Stefano Vicari, Deny Menghini

Abstract readCase Reports
In one paragraph

Article in Italian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Andrea BattistiChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Cristiana VaruzzaChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Giulia BrunozziChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Giulia LazzaroChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Pietro De RossiChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Stefano VicariChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy.
Deny MenghiniChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, IRCCS, 00146, Rome, Italy. deny.menghini@opbg.net.ORCID http://orcid.org/0000-0002-3459-2601

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, particular interest has been directed toward the topic of intellectual giftedness. An IQ above 130, typically assessed with standardized cognitive scales, is a widely recognized criterion for giftedness. Gifted children often face emotional and socio-relational difficulties, particularly anxiety, due to perfectionism and high-performance pressures. Co-occurring neurodevelopmental disorders like Attention-Deficit/Hyperactivity Disorder (ADHD) and Social (Pragmatic) Communication Disorder complicate their adaptation in various life contexts. This is the case of twice-exceptional children, who are those presenting intellectual giftedness alongside one or more disorders. ADHD, characterized by inattention, hyperactivity, and impulsivity, poses significant academic and social challenges, making accurate diagnosis and appropriate treatment in gifted individuals crucial. Similarly, Social (Pragmatic) Communication Disorder induces significant relational difficulties with peers, with potential deeply negative consequences for children’s psychological well-being. A thorough neuropsychological and emotional-behavioural assessment, along with personalized and holistic therapeutic approaches, are essential for optimal adaptation in all life contexts for twice-exceptional children. CASE PRESENTATION: The present study aimed to thoroughly characterize the neuropsychological and psychopathological profile of a gifted child to gain a deeper understanding of his overall well-being and to identify the need for a personalized intervention plan. Specifically, this case report describes a 7-year-and-8-month-old boy assessed due to attention difficulties, anxiety, socio-relational challenges, and behavioural concerns. The child underwent extensive neuropsychological and psychopathological evaluations. The study details his medical history, diagnostic formulation, pharmacological and behavioural interventions, and a six-month follow-up to monitor clinical progresses. Applied interventions demonstrated efficacy in addressing ADHD symptoms and various emotional-behavioural aspects. The positive progression of ADHD symptoms across various life contexts demonstrated the effectiveness of the proposed treatments and highlighted the appropriateness of the educational and environmental adjustments implemented within the school setting. In contrast, socio-relational difficulties have shown limited response to treatments and will require more targeted approaches.

conclusionsThe study underscores the importance of early and targeted interventions for twice-exceptional children to mitigate adverse outcomes. Emphasizing multidisciplinary interventions that engage diverse stakeholders across various contexts, our findings highlight the necessity of tailored approaches to ensure appropriate development and psychological well-being for gifted children with associated clinical conditions.

Indexed as

Anxiety DisordersAttention Deficit Disorder with HyperactivityChild, GiftedSocial Communication DisorderChildCombined Modality TherapyHumansMaleNeuropsychological TestsCognitive-behavioural therapyIntelligenceMethylphenidateNeurodevelopmental disordersPsychiatric disordersPsychological well-beingTwice-exceptional children

Identifiers

PMID41814369
PMCPMC13088565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.