ArticleBMC biotechnology2026
Polyurethane nanofibrous scaffolds for wound repair: from electrospinning fabrication to biological performance evaluation.
Article in BMC biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Green extraction routes for conversion of Nerium oleander L. biomass into bioactive agents: phytochemical insights and antimicrobial promise.BMC complementary medicine and therapies · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents the electrospinning fabrication of thermoplastic polyurethane (TPU) nanofibrous scaffolds with two fiber architectures; randomly oriented and unidirectionally aligned incorporating olive oil and copper oxide nanoparticles (CuO NPs) to enhance biomedical performance. Both scaffold types exhibited robust antibacterial activity: randomly oriented TPU/CuO mats produced inhibition zones of 33.0 mm against Staphylococcus aureus and 19.46 mm against Escherichia coli, whereas aligned mats showed a slight reduction to a 31.0 mm zone against S. aureus. Cytocompatibility assays using HFB4 fibroblasts demonstrated low cytotoxicity, with cell viability rates of 86% for randomly oriented fibers and 96.25% for aligned fibers. Whole-blood clotting tests confirmed rapid hemostatic action in both orientations, underscoring their capacity to promote blood coagulation. Collectively, these multifunctional TPU/CuO/olive oil nanofibrous membranes combine controlled fiber orientation with bioactive filler incorporation to deliver enhanced antimicrobial efficacy, superior cell compatibility, and effective hemostatic properties that position them as promising candidates for next-generation wound-healing dressings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.