Evidence map›Paper›PMID 41814258›Full record

ArticleBMC pulmonary medicine2026

Case Report: diagnosis of mixed Scedosporium apiospermum infection assisted by bronchoalveolar lavage fluid morphology.

Yuli Zhou, Daojun Yu, Shu Li, Senlin Ruan, Jun Ye, Danxia Zhou, Qiong Chen, Juan Jin, Kerui Song

Abstract readCase Reports
In one paragraph

Article in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuli ZhouDepartment of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, 310006, China.
Daojun Yu *Department of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, 310006, China.
Shu LiDepartment of Laboratory Medicine, Affiliated Henan Anyang city Hua county People's Hospital, Henan, 456400, China.
Senlin RuanDepartment of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, 310006, China.
Jun YeDepartment of Laboratory Medicine, Affiliated Zhejiang Qingtian County People's Hospital, Lishui, 323900, China.
Danxia ZhouDepartment of Laboratory Medicine, Affiliated Hainan Haikou People's Hospital, Haikou, 570100, China.
Qiong ChenDepartment of Laboratory Medicine, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, 310006, China.
Juan Jin *Department of Nephrology, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310000, China. lang_018@163.com.
Kerui SongDepartment of Nephrology, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, 310000, China. skr64049758@163.com.

Funding

The Construction Fund of Key Medical Disciplines of Hangzhou, Laboratory Diagnostics 2025HZZD01Zhejiang Science and Technology Plan for Disease Prevention and Control 2025JK256
6 · The paper itself

Abstract

backgroundScedosporium apiospermum is a highly aggressive opportunistic pathogen, widely distributed in natural environments. Infections predominantly occur in immunocompromised individuals but may also affect immunocompetent individuals with predisposing factors such as trauma, drowning, exposure to contaminated water, diabetes, or malnutrition. CASE PRESENTATION: In the reported case, morphological abnormalities were initially identified in bronchoalveolar lavage fluid (BALF). Subsequent microbial culture identification and metagenomic next-generation sequencing (mNGS) confirmed a mixed infection involving S. apiospermum.

conclusionsThis case highlights the importance of improving laboratory personnel’s morphological recognition of S. apiospermum in routine examinations. The combined use of multiple diagnostic methods enhances detection rates, shortens the time to identification, ensures timely and effective treatment for patients, and ultimately reduces mortality.

Indexed as

Bronchoalveolar Lavage FluidCoinfectionLung Diseases, FungalMycetomaScedosporiumAntifungal AgentsHumansInvasive Fungal InfectionsAntifungal AgentsAspergillusbronchiectasismorphology of alveolar lavage fluidScedosporium apiospermum

Identifiers

PMID41814258
PMCPMC13093943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.