Evidence map›Paper›PMID 41814183›Full record

ArticleBMC cardiovascular disorders2026

Echocardiographic evaluations of right ventricular functions and dimensions in children with bronchial asthma in Ile-Ife, Nigeria.

Hammed Hassan Adetola, Bankole Peter Kuti, Tinuade Adetutu Ogunlesi, John Akintunde Okeniyi, Perpetua Okwuchi Obiajunwa, Abiodun John Kareem

Abstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Hammed Hassan AdetolaMinistry of Health, Freetown, Sierra Leone.
Bankole Peter KutiDepartment of Paediatrics and Child Health, Wesley Guild Hospital, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun state, Nigeria.
Tinuade Adetutu OgunlesiDepartment of Paediatrics and Child Health, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun state, Nigeria.
John Akintunde OkeniyiDepartment of Paediatrics and Child Health, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun state, Nigeria.
Perpetua Okwuchi ObiajunwaDepartment of Paediatrics and Child Health, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Osun state, Nigeria.
Abiodun John KareemDepartment of Paediatrics, Federal Medical Centre, Owo, Ondo State, Nigeria. biodunkareem13@gmail.com.ORCID http://orcid.org/0000-0002-2565-0881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma is a chronic inflammatory airway disorder with cardiovascular effects. This study aimed to determine the relationship between right ventricular function and dimensions, and the severity of bronchial asthma.

methodsChildren aged 6–14 years with asthma were recruited for this comparative cross-sectional study. The severity of asthma and the level of symptom control were documented using GINA criteria. The lung function tests by spirometry, conventional echocardiography, and tissue Doppler echocardiography were performed.

resultsThe majority (71.2%) had mild intermittent asthma. The symptoms of asthma were well-controlled in 75.0% of participants. The mean right ventricle (RV) anterior wall thickness of children with asthma was significantly thicker than non-asthmatics [10.1 (1.3) vs 9.0 (1.3) mm; t = 5.709; p < 0.001]. The difference in the mean tricuspid ratio of the early to late diastolic velocities (tricuspid E’/A’) between the subjects [1.8 (0.4) mm] and control [2.0 (0.4) mm] was statistically significant [t = 1.980; p = 0.047] but the mean trans annular plane systolic excursion (TAPSE) in subjects, 23.4 (3.9) and the control, 23.4 (2.8) were similar and not statistically significant (t = 0.009, p = 0.990). The mean RV wall thickness in persistent asthma [10.5 (1.4)] was thicker than in intermittent asthma [9.8 (0.9)] and was statistically significant (t = 2.750; p = 0.006). The TAPSE (F = 4.010; p = 0.022), RV isovolumetric relaxation time (F = 10.380; p = 0.005), and tricuspid E’/A’ (F = 9.500; p = 0.008) significantly increased as the level of asthma symptom control worsened.

conclusionChildren with worsening asthma symptoms present with right ventricular dysfunction, hence a need for echocardiographic monitoring in children with asthma.

Indexed as

AsthmaEchocardiography, DopplerVentricular Dysfunction, RightVentricular Function, RightAdolescentAge FactorsCase-Control StudiesChildCross-Sectional StudiesFemaleHumansLungMaleNigeriaPredictive Value of TestsSeverity of Illness IndexAsthmaChildrenNigeriaRight ventricular function

Identifiers

PMID41814183
PMCPMC13093920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.