ArticleMagnetic resonance in medicine2026
Quantitative Diffusion and T2 Mapping Using RF-Modulated Phase-Based Gradient Echo Imaging.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Combined ADC and TMagnetic resonance in medicine · 2026Article
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5 authors.
Funding
Abstract
purposeTo introduce and evaluate the feasibility of a novel RF-phase modulated gradient echo (GRE) method for quantitative diffusion MRI, aimed at mitigating geometric distortion and enabling high-resolution 3D quantitative diffusion/T2 mapping as a complementary alternative to conventional DWI. THEORY AND
methodsThe proposed phase-based diffusion (PBD) method employs RF phase modulation to encode both diffusion and T2 information into the GRE signal phase. A closed-form analytical model enables joint apparent diffusion coefficient (ADC) and T2 mapping via iterative reconstruction. The method's feasibility was evaluated via Bloch equation simulations, phantom experiments, and preliminary in vivo imaging studies.
resultsMonte Carlo simulations revealed that PBD provides more accurate median ADC estimates at low signal-to-noise ratios (SNRs) compared to conventional single-shot echo-planar imaging (SS-EPI), although PBD exhibited greater variability. Phantom studies demonstrated good agreement for PBD-derived ADC values (e.g., R
conclusionPBD provides ADC and T2 maps with improved geometric fidelity in phantoms and in vivo, and offers robust median ADC estimates from noisy data based on simulations. This combination of spatial precision and noise characteristics makes PBD promising for applications such as high-resolution DWI for prostate MRI.
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