Evidence map›Paper›PMID 41814052›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Temporal snoring metrics and obstructive sleep apnea severity: nonlinear associations and data-driven inflection points in a clinical cohort.

Zhenxing Yu, Fen Wang, Zhipeng Zhang, Jing Zha, Cunlin Gong, Liying Deng, Jianglong Tu, Yongmin Ding

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Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Zhenxing Yu *Department of Neurosurgery, The 908th Hospital of the JointLogistic Support of the People's Liberation Army, Nanchang, China.
Fen Wang *Department of Neurophysiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhipeng ZhangDepartment of Neurosurgery, The 908th Hospital of the JointLogistic Support of the People's Liberation Army, Nanchang, China.
Jing ZhaDepartment of Radiology, The 908th Hospital of the Joint Logistic Support of the People's Liberation Army, Nanchang, China.
Cunlin GongDepartment of Neurosurgery, The 908th Hospital of the JointLogistic Support of the People's Liberation Army, Nanchang, China.
Liying DengDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jianglong TuDepartment of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Yongmin DingDepartment of Neurophysiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China. ndefy02029@ncu.edu.cn.ORCID http://orcid.org/0009-0004-0133-2637

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSnoring is a common marker of upper-airway obstruction. However, how the temporal load of snoring relates to OSA severity from non-OSA to severe disease across the full AHI spectrum remains incompletely understood.

methodsWe conducted a retrospective, single-center study of 1,423 adults who underwent overnight portable sleep monitoring (PSM; Type III HSAT). Temporal snoring features included snore frequency (events/night), mean snore duration (s), total snoring time (min/night), and the percentage of estimated sleep time spent snoring (%). The primary outcome was the device-derived apnea-hypopnea index (AHI) as a continuous measure of OSA severity. Associations were evaluated using multivariable linear regression, with non-linearity explored using smooth curve fitting (generalized additive models) and segmented (threshold) regression.

resultsIn fully adjusted models, higher snore event count and greater cumulative snoring burden (total snoring time and percentage of TST spent snoring) were associated with higher AHI. Mean snore duration showed an overall inverse association in linear models, while non-linear modeling indicated feature-specific patterns. Smooth curve fitting and segmented regression identified inflection points at ~ 15 s (mean duration), ~ 75.6 min/night (total snoring time), and ~ 24.3% and ~ 74.5% (snoring percentage). Subgroup analyses showed no interaction by sex; BMI modified the mean snore duration-AHI association, while associations for other snoring metrics were broadly consistent across BMI strata.

conclusionsTemporal snoring metrics derived from PSM were associated with device-derived AHI and exhibited feature-specific non-linear patterns with interpretable inflection points. These candidate thresholds are hypothesis-generating and are not intended as diagnostic cut-points; prospective PSG-based replication and external validation are required before clinical application.

Indexed as

Sleep Apnea, ObstructiveSnoringAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedNonlinear DynamicsPolysomnographyRetrospective StudiesSleep DurationApnea–hypopnea indexNon-linear associationObstructive sleep apneaPortable sleep monitoringSnoring

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.