ArticleArchives of osteoporosis2026
Fracture risk assessment in patients with ileal urinary diversion after radical cystectomy: a comprehensive evaluation integrating bone mineral density, trabecular bone score, and FRAX®.
Article in Archives of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We conducted a comprehensive fracture risk assessment in 112 men with urinary diversion (UD) after radical cystectomy, integrating bone mineral density (BMD), trabecular bone score (TBS), and FRAX®. A substantial proportion met the diagnostic criteria for osteoporosis or had lower TBS values. These findings support routine skeletal assessment during follow-up. PURPOSE: Patients undergoing radical cystectomy with UD face an increased risk of fracture; however, this aspect remains poorly investigated. We aimed to provide an integrated evaluation of skeletal health and fracture risk in men with UD.
methodsWe conducted a cross-sectional study of 112 men (mean age 70.6 ± 7.98 years; range 50-83) with ileal UD. BMD was measured using DXA, TBS was obtained from lumbar spine DXA images, and 10-year fracture risk was estimated using FRAX®. Logistic regression was used to identify predictors of osteoporosis and lower TBS values.
resultsOsteoporosis was identified in 32.1% of patients, and 40.2% were classified in the lowest TBS category (TBS < 1.23). Only 12.5% had normal results for both BMD and TBS. Median FRAX-MOF was 3.9% (IQR 2.7-6.05) without BMD, 5.3% (2.98-7.82) with BMD, and 5.8% (3.4-9.5) when adjusted for TBS. Median FRAX-HIP was 1.35% (0.7-2.78), 1.8% (0.9-4.55) with BMD, and 2% (1-5.2) with TBS adjustment. Age (per year, OR = 1.11, 95% CI 1.02-1.20; p = 0.012) and BMI (per kg/m
conclusionsMen with ileal UD showed reduced bone mass and a notable proportion of low TBS values, consistent with increased skeletal fragility and fracture risk. Structured bone health assessment should be considered during routine follow-up.
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