Evidence map›Paper›PMID 41814042›Full record

ArticleMolecular imaging and biology2026

Value of Imaging Parameters of [

Yihan Yan, Lifang Pang, Yibo He, Zhenghao Jiang, Yiqiu Zhang

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Article in Molecular imaging and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yihan Yan *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Lifang Pang *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yibo HeDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Zhenghao JiangDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
Yiqiu ZhangDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. zhang.yiqiu@zs-hospital.sh.cn.

Funding

Science and Technology Commission of Shanghai Municipality 23TS1401300
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the value of [

methodsThe study included 102 patients with ICC diagnosed between January 2018 and December 2022. All patients underwent preoperative [

resultsAmong the 102 patients with ICC, 60 (58.8%) patients had LNM while 42 patients (41.2%) were free of LNM. TBR(without LNM: 6.9 ± 3.6 vs. LNM: 8.2 ± 2.9, P = 0.019), CA19-9(506.9 ± 1602.7 vs. 1901.2 ± 3195.1, P = 0.011) and CEA(5.1 ± 8.9 vs. 32.5 ± 82.7, P = 0.035) in the LNM group were significantly higher than in the without LNM group. Three additional, statistically significant features, tumor TBR > 6.4, CA19-9 > 149.7 U/mL and CEA > 3.2 ng/mL, were integrated into a prediction model, which substantially outperformed use of the single parameter in ROC analysis (AUC 0.802 vs. 0.676, 0.671 and 0.656).

conclusionTBR > 6.4 and CA19-9 > 149.7 U/mL were identified as effective preoperative predictors of LNM in patients with ICC. The prognostic model we propose, integrating imaging parameters and serological indicators, significantly enhances predictive capability.

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaFluorodeoxyglucose F18Lymphatic MetastasisPositron Emission Tomography Computed TomographyAgedFemaleHumansMaleMiddle AgedROC CurveFluorodeoxyglucose F18Intrahepatic cholangiocarcinomaLymph node metastasisPET/CTSerological index

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.