Trial reportNature2026
Risk-adaptive therapy guided by dynamic ctDNA in nasopharyngeal carcinoma.
Abstract readClinical Trial, Phase IIMulticenter Study
In one paragraph
Trial report in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- The current role of immunotherapy in treating nasopharyngeal carcinoma.Human vaccines & immunotherapeutics · 2026Review
- Clinical metastatic cancer from initiation to colonization: emerging challenges and breakthroughs.Oncogene · 2026Review
- Review
- Epstein-Barr virus based biomarkers and targeted therapies in nasopharyngeal carcinoma: a narrative review.The Lancet regional health. Western Pacific · 2026Review
- Liquid biopsy to inform adjuvant decisions during neoadjuvant chemotherapy - a full-circle moment for nasopharyngeal cancer.Nature reviews. Clinical oncology · 2026Article
- Multidrug resistance in cancer: current understandings and future perspective.Molecular biomedicine · 2026Review
- A time-adapted risk stratification framework guided by longitudinal post-radiotherapy EBV DNA clearance for high-risk nasopharyngeal carcinoma patients.Radiation oncology (London, England) · 2026Article
- Long-term efficacy of traditional Chinese medicine combined with chemotherapy for advanced non-small cell lung cancer: a systematic review and meta-analysis of reconstructed individual patient data over 3 years.Frontiers in pharmacology · 2026Review
- Pan-immune-inflammation value predicts 2-year recurrence after chemoradiotherapy in nasopharyngeal carcinoma.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
42 authors.
Jiawei Lv *Department of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Dan-Xue Zheng *Department of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Jin-Hui Liang *Department of Radiation Oncology, Wuzhou Red Cross Hospital, Wuzhou, P. R. China.
Ning Zhang *Department of Radiation Oncology, First People's Hospital of Foshan, Foshan, P. R. China.
Zu-Lu Ye *Department of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Xu-Dong Xu *Department of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Melvin L K Chua *Duke NUS Medical School and Division of Radiation Oncology, National Cancer Centre, Singapore, Singapore.ORCID http://orcid.org/0000-0002-1648-1473
Lu-Lu ZhangDepartment of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Zi-Ming DuDepartment of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0003-2667-4989
Zi-Chen ZhangDepartment of Molecular Diagnostics, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Wen-Fei LiDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Ling-Long TangDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0002-8561-1454
Lei ChenDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Yan-Ping MaoDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0003-1027-071X
Rui GuoDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Yu-Pei ChenDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Li LinDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Yuan ZhangDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Xu LiuDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0003-4827-5524
Cheng XuDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Zhi-Xuan LiDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0002-8590-875X
Ling-Xin XuDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Pan-Yang YangDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Kun ChenDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China.
Deng BinDepartment of Radiation Oncology, Wuzhou Red Cross Hospital, Wuzhou, P. R. China.
Tian-Sheng GaoDepartment of Radiation Oncology, Wuzhou Red Cross Hospital, Wuzhou, P. R. China.
Jian-Ye YanDepartment of Radiation Oncology, Wuzhou Red Cross Hospital, Wuzhou, P. R. China.
Lu-Si ChenDepartment of Radiation Oncology, First People's Hospital of Foshan, Foshan, P. R. China.
Shao Hui HuangDepartment of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
Hong-Yun ZhaoDepartment of Medical Oncology and Clinical Research, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.ORCID http://orcid.org/0000-0002-1251-3888
Shu-Bin HongDepartment of Endocrinology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Yu-Sheng JieDepartment of Infectious Diseases, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Hui-Ling HuangDepartment of Cardiology, Cardiac Prevention and Assessment Center, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Xu-Hua TangDepartment of Dermatology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China.
Jing-Ping YunDepartment of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China.ORCID http://orcid.org/0000-0002-1001-0769
Li-Zhi LiuDepartment of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China.
Li TianDepartment of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China.
Hao-Jiang LiDepartment of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China.
Ji-Bin LiDepartment of Clinical Research, Sun Yat-sen University Cancer Centre, Guangzhou, P. R. China. lijib@sysucc.org.cn.ORCID http://orcid.org/0000-0001-7632-3648
Guan-Qun ZhouDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China. zhougq@sysucc.org.cn.ORCID http://orcid.org/0000-0002-7989-4224
Jun MaDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China. majun2@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-1137-9349
Ying SunDepartment of Radiation Oncology, Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Centre for Cancer, Guangzhou, P. R. China. sunying@sysucc.org.cn.ORCID http://orcid.org/0000-0002-5888-2929
Funding
Bayer
Abstract
Despite promising data showing that circulating tumour DNA (ctDNA) dynamics during treatment can inform real-time tumour response and recurrence risk
Indexed as
Circulating Tumor DNANasopharyngeal CarcinomaNasopharyngeal NeoplasmsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsChemoradiotherapyCisplatinDeoxycytidineDisease-Free SurvivalFemaleGemcitabineHumansMaleMiddle AgedNeoadjuvant TherapyCirculating Tumor DNACisplatinDeoxycytidineGemcitabine
Identifiers
PMID
41813900What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.