Evidence map›Paper›PMID 41813728›Full record

ArticleScientific reports2026

The association between anthropometric indices with non-alcoholic fatty liver in the Azar cohort population.

Elham Karimi, Reyhane Mokhtari Hemami, Mohammd Hossein Somi, Neda Gilani, Alireza Ostadrahimi, Masoud Shirmohamadi, Aarefeh Jafarzadeh Kohneloo, Shahrzad Tavakkoli, Elnaz Faramarzi, Mahdieh Safaei

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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10 authors.

Elham Karimi *Student research committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Reyhane Mokhtari Hemami *Student research committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammd Hossein SomiLiver and Gastrointestinal Diseases Research center, Tabriz University of Medical Sciences, Tabriz, Iran.
Neda GilaniDepartment of statistics and epidemiology, Faculty of Health, Tabriz university of medical Sciences, Tabriz, Iran.
Alireza OstadrahimiNutrition Research Center, Tabriz university of medical Sciences, Tabriz, Iran.
Masoud ShirmohamadiLiver and Gastrointestinal Diseases Research center, Tabriz University of Medical Sciences, Tabriz, Iran.
Aarefeh Jafarzadeh KohnelooDepartment of statistics and epidemiology, Faculty of Health, Tabriz university of medical Sciences, Tabriz, Iran.
Shahrzad TavakkoliStudent research committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Elnaz Faramarzi *Liver and Gastrointestinal Diseases Research center, Tabriz University of Medical Sciences, Tabriz, Iran. elnazfaramarzi849@gmail.com.
Mahdieh Safaei *Student research committee, Tabriz University of Medical Sciences, Tabriz, Iran. safaei.mahdieh156@gmail.com.

Funding

Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Grant number 700/108
6 · The paper itself

Abstract

Based on the findings of previous studies, inconsistencies persist in the literature regarding the most reliable anthropometric indices for screening non-alcoholic fatty liver disease (NAFLD). Therefore, the aim of this study was to evaluate the most effective anthropometric indices for predicting NAFLD in the Azar cohort population. In this cross-sectional study, data from the Azar cohort study were utilized. Various anthropometric indices, including visceral adiposity index (VAI), weight-adjusted waist index (WWI), abdominal volume index (AVI), body adiposity index (BAI), body roundness index (BRI), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR), were calculated for 14,915 participants. We categorized anthropometric measurements into two groups: conventional and novel anthropometric indices. Conventional indices include body mass index (BMI), waist circumference (WC), wrist circumference (WrC), hip circumference (HC), WHR, WHtR, and novel indices include BRI, ABI, AVI, VAI, and WWI. Our findings indicated that all conventional and novel anthropometric indices were significantly associated with NAFLD. The highest odd for NAFLD was WHtR ≥ 0.5 (4.76), then BMI ≥ 25 (3.27), followed by WHR and WC (2.79, 2.65 respectively). A comparison of the odds of conventional and novel anthropometric indices for NAFLD revealed that the odds for BMI, WhtR, WHR and WC are higher than those for the novel indices. While the most sensitive AUC outcomes for screening NAFLD were observed for the AVI (80.80) and BRI (79.01). The AVI and BRI cut-off points for determining NAFLD were established at 17.31 for AVI and 4.85 for BRI. Ultimately, BMI, WC, WHR, AVI, BRI, and VAI were the most effective anthropometric indices for predicting NAFLD in the Azar cohort population. In conclusion, our study suggests that novel anthropometric indices might be useful markers for detecting NAFLD in adults, alongside conventional anthropometric measures.

Indexed as

AnthropometryEastern European PeopleNon-alcoholic Fatty Liver DiseaseAdiposityAdultBody Mass IndexCohort StudiesFemaleHumansIntra-Abdominal FatIranMaleMiddle AgedWaist CircumferenceWaist-Hip RatioAbdominal volume indexBody mass indexNAFLDVisceral adiposity indexWaist circumferenceWeight-adjusted waist index

Identifiers

PMID41813728
PMCPMC13102924

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