Evidence map›Paper›PMID 41813609›Full record

ArticleJournal of the science of food and agriculture2026

Characterization, in vitro release, and antioxidant activity of glutenin hydrolysate encapsulated in liposome-loaded uni-axial and co-axial electrospun fibers.

Nagihan Kalintas Caglar, Ahmet Furkan Caglar, Fatih Bozkurt, Feyzanur Izciler, Osman Sagdic, Canan Yagmur Karakas, Ayse Karadag

Abstract read
In one paragraph

Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nagihan Kalintas CaglarDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Ahmet Furkan CaglarDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Fatih BozkurtDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.ORCID https://orcid.org/0000-0003-4905-095X
Feyzanur IzcilerDepartment of Food Engineering, Faculty of Engineering, Inonu University, Malatya, Turkey.
Osman SagdicDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Canan Yagmur KarakasDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.
Ayse KaradagDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-8615-7321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBioactive peptides derived from protein hydrolysates provide various health benefits; however, their practical application is limited by low gastrointestinal stability, enzymatic degradation, and poor intestinal absorption. Overcoming these challenges remains a key bottleneck for oral peptide delivery. This study aimed to develop and systematically compare uni-axial and co-axial electrospun pullulan/carboxymethylcellulose fibers incorporating liposome-encapsulated glutenin hydrolysate (GH) to enhance its stability, mucoadhesion, and controlled release along the gastrointestinal system.

resultsGH (7.5 mg mL

conclusionThe hybrid liposome-nanofiber approach integrates protective and controlled-delivery mechanisms, resulting in enhanced preservation of antioxidant activity and sustained release compared with conventional fibers. This food-grade strategy shows strong potential for oral delivery of bioactive peptides in functional food and nutraceutical applications requiring gastrointestinal stability. © 2026 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AntioxidantsDrug CompoundingDrug Delivery SystemsGlutensProtein HydrolysatesDelayed-Action PreparationsGlucansHumansLiposomesNanofibersAntioxidantsDelayed-Action PreparationsGlucansGlutensLiposomesProtein Hydrolysatespullulandigestionelectrospinningmucoadhesionpeptide

Identifiers

PMID41813609
PMCPMC13157244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.