Evidence map›Paper›PMID 41813604›Full record

ArticleProteins2026

A Machine Learning Approach to Predict Functional Performance From Measurable Protein Structural Characteristics: A Screening Tool for Protein Ingredient Quality.

Ronit Mandal, Sara Malvar, Ranveer Chandra, Baraem P Ismail

Abstract read
In one paragraph

Article in Proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ronit MandalDepartment of Food Science and Nutrition, University of Minnesota, Saint Paul, Minnesota, USA.ORCID https://orcid.org/0000-0003-3541-8039
Sara MalvarMicrosoft Corporation, One Microsoft Way, Redmond, Washington, USA.
Ranveer ChandraMicrosoft Corporation, One Microsoft Way, Redmond, Washington, USA.
Baraem P IsmailDepartment of Food Science and Nutrition, University of Minnesota, Saint Paul, Minnesota, USA.ORCID https://orcid.org/0000-0002-3551-8446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The food industry is witnessing the emergence of specialized protein-based functional ingredients for the use as gelling, thickening, and/or emulsifying agents in various food applications. Different sources of protein including species and cultivars, as well as variable processing conditions affect the protein's structural characteristics, which in turn govern their functional properties. The complex relationship between the structure and function of the protein can be modeled using machine learning (ML) algorithms. In this study, different ML algorithms were used to predict solubility, emulsifying activity index, emulsifying capacity, and gel strength of different plant proteins using structural predictors (surface hydrophobicity, zeta potential, undenatured protein content, water holding capacity, soluble protein polymer content, β-sheet content). Model performances were assessed by specific metrics (

Indexed as

Emulsifying AgentsMachine LearningPlant ProteinsAlgorithmsHydrophobic and Hydrophilic InteractionsPrediction AlgorithmsPredictive Learning ModelsSoft ComputingSolubilityEmulsifying AgentsPlant Proteinsfunctional propertiesmachine learningplant proteinsregression

Identifiers

PMID41813604
PMCPMC13327453

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.