Evidence map›Paper›PMID 41813165›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2026

Surgical Outcomes and Prognostic Impact of Lung Cancer Associated with Cystic Airspaces: A Retrospective Analysis of 75 Cases.

Yuichiro Machida, Kento Suzuki, Mitsunobu Ino, Takumi Sonokawa, Norihito Kawasaki, Jitsuo Usuda

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Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

6 authors.

Yuichiro MachidaDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Kento SuzukiDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Mitsunobu InoDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Takumi SonokawaDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Norihito KawasakiDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.
Jitsuo UsudaDepartment of Thoracic Surgery, Nippon Medical School, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present study reviewed surgical cases of lung cancer associated with cystic airspace (LCCA) and examined the imaging and clinicopathological features of these cases.

methodsA total of 75 patients with lung cancer associated with cystic airspace, who underwent lung cancer surgery in our hospital between January 2017 and December 2020, were included. We retrospectively analyzed the association between postoperative recurrence of lung cancer and lung cancer associated with the cystic airspace using the Cox proportional hazards model.

resultsPatients with LCCA had a worse prognosis than those with non-LCCA. Furthermore, a univariate analysis showed a significant difference between sex, smoking, differentiation, tumor size, Stage, and LCCA, while a multivariate analysis showed a significant difference between Stage and LCCA. LCCA cases were classified into four categories, as reported in a previous study. Types I and III showed more adenocarcinomas, while Type IV tended to show squamous cell carcinomas.

conclusionsLCCA has a poor prognosis. It is often difficult to determine which of the T factors of the TNM classification are applied. Therefore, further studies are needed to accumulate more LCCA cases.

Indexed as

CystsLung NeoplasmsPneumonectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment Outcomelung cancer associated with cystic airspacesurgical resection

Identifiers

PMID41813165
PMCPMC12989256

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