Evidence map›Paper›PMID 41812661›Full record

ArticleCell2026

Papuan admixture predated the settlement of Palau.

Yue-Chen Liu, Joanne Eakin, Jolie Liston, Rosalind Hunter-Anderson, Calvin Emesiochel, Kiblas Soaladaob, Sunny O Ngirmang, Olivia Cheronet, Carla S Hadden, Alexander Cherkinsky and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yue-Chen LiuKey Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA; Department of Genetics, Harvard Medical School, Boston, MA, USA. Electronic address: liuyuechen@ivpp.ac.cn.
Joanne EakinAlbuquerque, NM, USA. Electronic address: jeeakin@gmail.com.
Jolie ListonPalau and Micronesian Heritage Consulting, LLC., Koror, Republic of Palau.
Rosalind Hunter-Anderson1513 Wellesley Dr NE, Albuquerque, NM 87106, USA.
Calvin EmesiochelPalau Bureau of Cultural and Historical Preservation, Koror, Republic of Palau.
Kiblas SoaladaobPalau Bureau of Cultural and Historical Preservation, Koror, Republic of Palau.
Sunny O NgirmangPalau Bureau of Cultural and Historical Preservation, Koror, Republic of Palau.
Olivia CheronetDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria; Human Evolution and Archaeological Sciences, University of Vienna, Vienna, Austria.
Carla S HaddenCenter for Applied Isotope Studies, University of Georgia, Athens, GA, USA.
Alexander CherkinskyCenter for Applied Isotope Studies, University of Georgia, Athens, GA, USA.
Matthew SpriggsVanuatu National Museum, Vanuatu Culture Centre, Port Vila, Vanuatu; School of Archaeology and Anthropology, Australian National University, Canberra, ACT, Australia.
Keith M PruferDepartment of Anthropology, University of New Mexico, Albuquerque, NM, USA; Center for Stable Isotopes, University of New Mexico, Albuquerque, NM, USA.
Swapan MallickDepartment of Genetics, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Ron PinhasiDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria; Human Evolution and Archaeological Sciences, University of Vienna, Vienna, Austria. Electronic address: ron.pinhasi@univie.ac.at.
David ReichDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA; Department of Genetics, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA. Electronic address: reich@genetics.med.harvard.edu.

Funding

Solving ascertainment bias in ancient DNA using Ultima Genomics sequencingR01HG012287 · NHGRI · HARVARD MEDICAL SCHOOL · PI REICH, DAVID E · 2021 to 2025
$2.7M
Howard Hughes Medical InstituteNHGRI NIH HHS R01 HG012287
6 · The paper itself

Abstract

The first people reached Remote Oceania 3,000 years before present (BP), arriving roughly simultaneously in the southwest Pacific, the Marianas Archipelago, and Palau. However, no genome-wide ancient DNA data have been available from Palau, a gap we address by reporting 21 individuals from four archaeological sites dating between 2,900 and 500 BP. All had approximately 60% ancestry related to East Asians and 40% to Papuans, similar to present-day Palauans, the longest stretch of population continuity anywhere in Remote Oceania. The lengths of contiguous Papuan ancestry segments in the oldest individuals show that major admixture between Papuans and East Asians in the ancestors of all sampled Palauans began prior to first settlement. This differs from the pattern in the southwest Pacific, where sampled individuals of the Lapita archaeological culture from three different islands had almost entirely East Asian ancestry, with large amounts of Papuan admixture observed only hundreds of years later.

Indexed as

Asian PeopleAsia, EasternDNA, AncientHumansPalauDNA, Ancientancient DNAAustronesianfirst Remote OceaniansMicronesiaPalau

Identifiers

PMID41812661
PMCPMC13025617

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.