Evidence map›Paper›PMID 41812376›Full record

ArticleThe journal of nutrition, health & aging2026

Adherence to various dietary quality indices of centenarian offspring in the New England Centenarian Study.

Erfei Zhao, Emma Schluter, Naglaa H El-Abbadi, M Kyla Shea, Nicola M McKeown, Paul F Jacques, Hannah J Lords, Stacy L Andersen, Thomas T Perls, Paola Sebastiani and 1 more

Abstract read
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Article in The journal of nutrition, health & aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Erfei ZhaoJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States.
Emma SchluterHarvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA, United States.
Naglaa H El-AbbadiJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States.
M Kyla SheaJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States.
Nicola M McKeownSargent College of Health & Rehabilitation Sciences, Boston University, Boston, MA, United States.
Paul F JacquesJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States.
Hannah J LordsDepartment of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, United States.
Stacy L AndersenDepartment of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, United States.
Thomas T PerlsDepartment of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, United States.
Paola SebastianiInstitute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, United States; Department of Medicine, School of Medicine, Tufts University, Boston, MA, United States.
Andres V Ardisson KoratJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States; Department of Medicine, School of Medicine, Tufts University, Boston, MA, United States. Electronic address: andres.ardisson_korat@tufts.edu.

Funding

Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategiesUH3AG064704 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI PERLS, THOMAS T, SEBASTIANI, PAOLA · 2022 to 2025
$14.7M
NIA NIH HHS UH3 AG064704
6 · The paper itself

Abstract

backgroundMany centenarian offspring (CO) show survival and health advantages compared to population controls, yet little is known about their dietary patterns. The New England Centenarian Study (NECS) offers an opportunity to characterize diet quality in this unique longevity-enriched population.

objectiveTo characterize overall and component-level diet quality among CO in the New England Centenarian Study (NECS) using four established indices and to contextualize these patterns relative to published benchmarks from large U.S. cohorts of older adults.

designWe analyzed data from 457 NECS participants who completed a 131-item food frequency questionnaire in 2005. We computed dietary scores using the Alternative Healthy Eating Index (AHEI), Healthy Eating Index (HEI), Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, and Planetary Health Diet Index (PHDI). We performed linear regression to examine whether these scores differ by sex, age, education, and marital status.

resultsParticipants' mean (SD) age was 73.6 (9.2) years; 55.1% were women. Overall mean (SD) index scores were: AHEI 51.9 (11.0), HEI 70.1 (9.2), MIND 8.6 (1.9), and PHDI 87.1 (12.0), indicating moderate overall diet quality. NECS participants generally met or approached targets for intakes of fruits, greens/beans, and protein-food quality (including seafood), as well as for moderation components such as sodium, added sugar, and refined grains. However, they fell short on intakes of legumes/soy/nuts and whole grains. Compared with nationally representative studies, NECS participants had modestly higher overall dietary scores across the four indices (P < 0.001). NECS participants had higher component scores for intakes of fruits, vegetables, and omega-3 s, but lower scores for whole grains, legumes, and soy. Higher education was consistently associated with healthier diet scores, while younger age and female sex corresponded to more favorable component patterns.

conclusionCentenarian offspring exhibit moderately higher diet quality than average U.S. older adults, with clear strengths and persistent gaps. These findings provide the first reference profile of dietary patterns in a longevity-enriched population and establish a foundation for future longitudinal research on the interaction of nutrition with inherited resilience to support healthy aging.

Indexed as

DietDiet, HealthyFeeding BehaviorAgedAged, 80 and overDiet, MediterraneanDiet SurveysFemaleFruitHumansLongevityMaleNew EnglandCentenarian offspringDietary quality indexFood Frequency Questionnaire (FFQ)Healthy agingLongevityNutrition

Identifiers

PMID41812376
PMCPMC12993191

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.