Evidence map›Paper›PMID 41811782›Full record

ArticleCanadian journal of gastroenterology & hepatology2026

Short- and Long-Term Healthcare Costs Attributable to Hepatitis B Among Newcomers to Ontario, Canada: A Matched Cohort Study.

Kikanwa Anyiwe, Jordan J Feld, Eleanor Pullenayegum, William W L Wong, Lena Nguyen, Beate Sander

Abstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kikanwa AnyiweInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, utoronto.ca.
Jordan J FeldToronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada, uhn.ca.ORCID 0000-0003-2640-2211
Eleanor PullenayegumChild Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada, sickkids.ca.
William W L WongInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, utoronto.ca.
Lena NguyenICES, Toronto, Ontario, Canada, ices.on.ca.
Beate SanderInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada, utoronto.ca.ORCID 0000-0003-2128-9133

Funding

Canada Research Chairs CRC-2022-00362Ontario Graduate ScholarshipOntario Ministry of Health and Long-Term Care
6 · The paper itself

Abstract

backgroundHealthcare expenditures across the clinical trajectory of hepatitis B virus (HBV) infection are inadequately characterized, particularly among immigrants. Our aim is to quantify HBV-attributable short- and long-term costs among a population of newcomers to the province of Ontario.

methodsWe performed a cost-of-illness study with an incidence-based, matched cohort design, employing linked population-based laboratory and health administrative data, and permanent residence data from Immigration, Refugees and Citizenship Canada (IRCC). We identified newcomers diagnosed with HBV between January 1, 2004, and December 31, 2018, and dichotomized the study cohort into individuals with or without liver complications before diagnosis. We used propensity score matching and phase-of-care costing to quantify monthly attributable costs for each of six HBV phases and longitudinal costs for one, five, and ten years following diagnosis. Costs were quantified in 2021 Canadian dollars.

resultsAmong n = 30,677 newcomers with HBV, 2.7 percent had complications before diagnosis. Mean monthly phase costs were higher for individuals with complications before diagnosis relative to those without for prediagnosis care ($439, 95% CI: $250-$645 vs. $22, 95% CI: $12-$34), initial care for HBV ($1545, 95% CI: $1196-$1945 vs. $331, 95% CI: $299-$369), continuing care for HBV ($537, 95% CI: $314-$760 vs. $73, 95% CI: $55-$92), and final care ($7271, 95% CI: $3749-$10,747 vs. $3430, 95% CI: $1813-$5061).

conclusionsFindings emphasize the dynamic nature of HBV-attributable costs and highlight the importance of care following diagnosis and complication onset.

Indexed as

Cost of IllnessEmigrants and ImmigrantsHealth Care CostsHepatitis BHepatitis B, ChronicAdultAgedCohort StudiesFemaleHealth ExpendituresHumansMaleMiddle AgedOntarioRefugeescost-of-illnesshealth economicshealth expendituresphase-of-care costingviral hepatitis

Identifiers

PMID41811782
PMCPMC13580811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.