Evidence map›Paper›PMID 41811682›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Association Between Visual Acuity and Cycloplegic Refractive Error in 3- to <10-Year-Old Children.

Jennifer X Haensel, Angela M Chen, Aparna Raghuram, Vivian M Manh, Susan A Cotter, Lisa A Jones-Jordan, Silvia Han, Ingryd Lorenzana, Kristine Huang, Reena Patel and 3 more

Abstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer X HaenselSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, California, USA. jhaensel@stanford.edu.
Angela M ChenSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Aparna RaghuramBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Vivian M ManhSeattle Children's Hospital, Seattle, Washington, USA.
Susan A CotterSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Lisa A Jones-JordanThe Ohio State University College of Optometry, Columbus, Ohio, USA.
Silvia HanSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Ingryd LorenzanaAdvanced Vision Center, Schaumburg, llinois, USA.
Kristine HuangSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Reena PatelSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Amy A LytleSnowy Range Vision Center, Laramie, Wyoming, USA.
Dashaini RetnasothieSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California, USA.
Tawna L RobertsSpencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, California, USA.

Funding

Afferent and Efferent Visual Systems During Abnormal Vision DevelopmentR01EY029307 · NEI · STANFORD UNIVERSITY · PI ROBERTS, TAWNA · 2020 to 2024
$3.0M
NEI NIH HHS R01 EY029307NEI NIH HHS R01-EY029307
6 · The paper itself

Abstract

purposeDistance visual acuity (VA) has been associated with refractive error in older children, but less is known about children <6 years of age and those without a history of refractive correction. This study examined the utility of VA testing and its relationship to refractive error in children aged 3 to <10 years without a history of refractive correction.

methodsUnaided monocular distance VA testing was performed at 3 m (age 3-6 years: ATS-HOTV chart; 7-<10 years: E-ETDRS chart) and near VA at 40 cm (ATS-4 Near VA). Cycloplegic autorefraction was used to categorise participants as myopic (sphere ≤ -0.75 dioptres (D)), hyperopic (sphere ≥2 D), astigmatic (cylinder ≥1.50 D) and emmetropic (< 0.75 D myopia and <2 D hyperopia). Receiver operating characteristic curves assessed the utility of VA testing in classifying children by refractive error type. Linear regressions examined the predictive value of refractive error magnitude in determining distance and near VA while accounting for age.

resultsOf 358 children, 84 (23.5%) had hyperopia, 30 (8.4%) myopia, 39 (10.9%) astigmatism and 229 (64.0%) emmetropia. Reduced distance VA was associated with myopia (area under the curve (AUC) = 91%, optimal cut-off = 0.15 logMAR) and astigmatism (AUC = 87%, cut-off = 0.25 logMAR), but not hyperopia (AUC = 63%, cut-off = 0.05 logMAR). Near VA showed only mildly higher performance for hyperopia (AUC = 70%, cut-off = 0.15 logMAR). For every 0.36 D increase in myopia, distance VA declined by 0.10 logMAR (p < 0.001). Distance and near VA were not predicted by the magnitude of hyperopia (distance: p = 0.30; near: p = 0.30) or astigmatism (distance: p = 0.35; near: p = 0.06).

conclusionIn children 3 to <10 years of age without prior refractive correction, reduced distance VA was associated with myopia and astigmatism, but not hyperopia; an incremental decline in VA with increasing refractive error magnitude was seen only in myopia.

Indexed as

MydriaticsRefraction, OcularRefractive ErrorsVisual AcuityChildChild, PreschoolFemaleHumansMaleROC CurveVision TestsMydriaticsCycloplegiaRefractive errorVisual acuityVisual acuity testing

Identifiers

PMID41811682
PMCPMC13279687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.