Evidence map›Paper›PMID 41811536›Full record

ArticleDiscover oncology2026

The evolution of real-world evidence in lung cancer: a bibliometric analysis from 2009 to 2024.

Ke-Ke Liu, Meng-Ke Wang, Ting-Ting Hou, Wei-Jing Gong, San-Lan Wu

Abstract read
In one paragraph

Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ke-Ke LiuDepartment of Pharmacy, Huaihe Hospital of Henan University, Kaifeng, 475000, Henan, China.
Meng-Ke WangDepartment of Pharmacy, Huaihe Hospital of Henan University, Kaifeng, 475000, Henan, China.
Ting-Ting HouDepartment of Pharmacy, Huaihe Hospital of Henan University, Kaifeng, 475000, Henan, China.
Wei-Jing GongDepartment of Pharmacy, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, 434000, Hubei, China. weijinggong@hust.edu.cn.
San-Lan WuDepartment of Pharmacy, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, 434000, Hubei, China. wusanlan@hust.edu.cn.

Funding

China International Medical Foundation Z-2021-46-2101-2023Chinese Pharmaceutical Association Hospital Pharmacy Department CPA-Z05-ZC-2023002Hubei Provincial Natural Science Foundation of China 2020CFB388National Natural Science Foundation of China 82003868
6 · The paper itself

Abstract

purposeReal-world evidence (RWE) plays an increasingly important role in complementing randomized controlled trials (RCTs) in lung cancer research. This study aims to map the knowledge structure, identify research trends, and highlight future directions of real-world studies (RWS) in lung cancer through bibliometric analysis.

methodsWe retrieved publications on RWS in lung cancer from the Web of Science Core Collection (WOSCC) spanning 2009 to 2024. Bibliometric analyses were performed using CiteSpace, VOSviewer, and the R package Bibliometrix to examine publication trends, collaborative networks, co-citation patterns, and keyword bursts.

resultsA total of 2,137 articles were included. Annual publications increased markedly after 2017, accounting for 97.52% of the total. China contributed the most publications (n = 660), while the USA exhibited the highest centrality in international collaboration. Keyword burst detection identified “combination therapy,” “KRAS mutation,” and “deep learning” as the most current research frontiers.

conclusionsThis analysis underscores the pivotal role of RWE in complementing RCTs and validating therapeutic strategies in oncology. Current frontiers include combination therapy, KRAS mutations, and deep learning, indicating a shift toward precision oncology and advanced data analytics.

Indexed as

BibliometricsLung cancerReal world evidenceResearch trendsVisualization analysis

Identifiers

PMID41811536
PMCPMC13096442

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.