Evidence map›Paper›PMID 41811523›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2026

Abdominal wall muscle remodeling after open transversus abdominis release: a CT-based analysis.

Jessica Zilberman Macret, Pedro Henrique de Freitas Amaral, Eduardo Rullo Maranhão Dias, João Paulo Venâncio de Carvalho, Giovanna Zucchini Rondini, Sergio Roll

Abstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica Zilberman MacretSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil. jemacret@uol.com.br.ORCID http://orcid.org/0000-0003-2764-4597
Pedro Henrique de Freitas AmaralSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-3999-210X
Eduardo Rullo Maranhão DiasSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9679-1887
João Paulo Venâncio de CarvalhoSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6716-3793
Giovanna Zucchini RondiniSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-8473-2713
Sergio RollSanta Casa de Sao Paulo - Abdominal Wall Surgery Unit, Rua Cesário Mota Júnior, 112 - Vila Buarque, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4381-5969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate abdominal wall muscle remodeling after posterior component separation using the transversus abdominis release (TAR) technique, and to explore potential associations between muscle remodeling and clinical, demographic, and anatomical variables.

methodsThis retrospective study included adults with incisional ventral hernia who underwent abdominal wall reconstruction with TAR between 2019 and 2023. Pre- and postoperative abdominal CT scans (≥ 6 months) were analyzed to measure bilateral cross-sectional areas of the rectus abdominis (RA), internal oblique (IO), and external oblique (EO) muscles at L3–L4 level. Percentage variation in muscle cross-sectional area (CSA), calculated using bilateral mean values, was used to characterize morphometric remodeling. Associations with demographic factors, clinical variables, hernia characteristics, and postoperative outcomes were assessed using Wilcoxon and Spearman tests.

resultsThirty-seven patients met inclusion criteria. Paired analyses demonstrated a consistent postoperative increase in CT-derived muscle CSA across RA, IO, and EO (all p < 0.001). In exploratory analyses, no demographic, clinical, or anatomic variable demonstrated a statistically significant association with bilateral mean muscle remodeling.

conclusionPatients undergoing open TAR demonstrate consistent postoperative abdominal wall morphometric remodeling on CT, characterized by RA expansion and coordinated changes in the oblique muscles following midline restoration. The clinical significance of these imaging findings remains uncertain and warrants prospective studies integrating functional outcomes.

Indexed as

Abdominal MusclesAbdominal WallHernia, VentralHerniorrhaphyIncisional HerniaAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedAbdominal wall reconstructionComplex ventral herniaComputed tomographyMuscle remodelingTransversus abdominis release

Identifiers

PMID41811523
PMCPMC12979404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.