Evidence map›Paper›PMID 41811510›Full record

ArticleDie Naturwissenschaften2026

Development of an eco-friendly larvicidal agent from Chrozophora oblongifolia against the dengue disease vector: antimicrobial and phytochemical analysis.

Hanan K Alghibiwi, Abadi M Mashlawi, Naifa Alenazi, Hussam M Shubaily, Amani Alhejely, Amal Naif Alshammari, Lama A Alshabani, Salama A Salama

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Article in Die Naturwissenschaften, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanan K AlghibiwiPharmacology and Toxicology Department, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Abadi M MashlawiDepartment of Biology, College of Science, Jazan University, P.O. Box. 114, 45142, Jazan, Saudi Arabia.
Naifa AlenaziDepartment of Pharmaceutical Science, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
Hussam M ShubailyBasic Medical Sciences Department, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Amani AlhejelyBiology Department, Darb University College, Jazan University, Jazan, Saudi Arabia.
Amal Naif AlshammariBiology Department, Darb University College, Jazan University, Jazan, Saudi Arabia.
Lama A AlshabaniDepartment of Pharmaceutical Science, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.ORCID http://orcid.org/0009-0004-5460-3330
Salama A SalamaDepartment of Biology, College of Science, Jazan University, P.O. Box. 114, 45142, Jazan, Saudi Arabia. sasalama@jazanu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever, a viral disease caused by the dengue virus, is transmitted via the bite of Aedes aegypti mosquito. Dengue is an endemic disease in more than a hundred countries. It is a global public health concern with 390 million infections occurring every year. An estimated 500,000 of these cases develop into severe dengue, resulting in approximately 25,000 deaths annually. The failure of chemical insecticides to combat and control mosquitoes, due to widespread resistance, creates an urgent need to search for effective natural alternatives. Chrozophora oblongifolia is an herbal and medicinal plant that has many pharmacological activities. In this study, we evaluated the efficacy of methanolic and acetone leaf extracts of C. oblongifolia plant against 3rd instar larvae and adults of Ae. aegypti mosquito using five concentrations ranging from 125-1000 mg/L. Mortality rates for the larval, pupal, and adult stages resulting from the larval treatment were recorded. Methanolic and acetone extracts exhibited lethal toxic effects on larvae, pupae, and adults. Both extracts showed complete larval mortality by 100% at the highest concentration of 1000 mg/L. The methanolic extract showed greater efficacy with LC

Indexed as

AedesAnti-Infective AgentsDengueInsecticidesMosquito VectorsPhytochemicalsPlant ExtractsAnimalsLarvaPlant LeavesAnti-Infective AgentsInsecticidesPhytochemicalsPlant ExtractsAcetoneAedes aegypti mosquitoCandida albicansChrozophora oblongifolia plantDengue feverEscherichia coliGas Chromatographic-mass spectroscopy (GC–MS)MethanolStaphylococcus aureus

Identifiers

PMID41811510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.