SynthesisInternational urogynecology journal2026
Regenerative Medicine Approaches for Female Stress Urinary Incontinence: A Systematic Review on the Evolving Roles of Stem Cells and Platelet-Rich Plasma.
Synthesis in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- IGF-1 Increases Collagen Deposition by Dermal Fibroblasts: Applications for Tissue Engineering.Cells · 2026Article
- Regenerative Medicine Approaches to Stress Urinary Incontinence.Biomimetics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStress urinary incontinence (SUI), characterized by involuntary urine leakage, significantly impairs quality of life and often stems from urethral sphincter insufficiency. While conventional treatments offer relief for many, they have limitations or may be unsuitable for certain patient populations. Regenerative medicine offers a transformative approach by focusing on the restoration of damaged tissue integrity and physiological function.
objectivesThis systematic review delves into the current understanding and therapeutic potential of two prominent regenerative strategies: stem cell therapy (SCT) and platelet-rich plasma (PRP). MATERIALS AND
methodsLiterature research backdated from 2010 using databases like PubMed, Cochrane Library and Clarivate Web of Science.
resultsFourteen studies focusing on the roles of SCT and PRP were included.
conclusionBoth modalities seem to show a promising effect in treatment of SUI in women and favourable safety profiles. They aim to regenerate compromised tissues and enhance sphincter function through distinct, yet potentially synergistic, biological mechanisms. We discuss their scientific rationale, summarize existing preclinical and clinical evidence, and highlight critical challenges, including the need for standardization and robust randomized controlled trials. The integration of these biologic interventions signifies a new frontier in SUI management, promising durable, minimally invasive, and biologically reconstructive solutions.
Indexed as
Identifiers
41811470What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.