Evidence map›Paper›PMID 41811454›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Conserved use of tetraspanin CD9 as an entry receptor by rhabdoviruses spanning multiple genera.

Wanwan Zhang, Bingbing Sun, Hao Huang, Junyu Chen, Ying'an Liang, Wenxi Li, Qinyu Peng, Ping Zhang, Zhipeng Zhan, Xiaogang Yang and 7 more

Erratum issuedAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Wanwan Zhang *School of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.ORCID 0000-0001-7058-9664
Bingbing Sun *School of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.ORCID 0009-0005-0726-9808
Hao HuangSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Junyu ChenSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Ying'an LiangDepartment of Immunology and Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Wenxi LiSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Qinyu PengDepartment of Immunology and Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0009-0008-3840-9086
Ping ZhangDepartment of Immunology and Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Zhipeng ZhanSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Xiaogang YangSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Lan YaoSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Huiquan ChenSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.ORCID 0000-0003-1988-3571
Eran BacharachThe Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0001-8341-2833
Haifeng LiSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.
Changjun GuoState Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0003-3223-6176
Meisheng YiSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.ORCID 0000-0003-1794-2734
Kuntong JiaSchool of Marine Sciences, Sun Yat-sen University, Zhuhai 519082, China.ORCID 0000-0001-7674-9454

Funding

GDSTC | Guangdong Special Support Plan () NIQN2024002GDSTC | Natural Science Foundation of Guangdong Province () 2023B1515120074; 2024A1515010880MOST | National Key Research and Development Program of China (NKPs) 2024YFD2401504MOST | National Natural Science Foundation of China (NSFC) 32473189 32173001 and 32273115national natural science and Israel foundation 32561143026Open Project program of state key laboratory biocontrol 2023SKLBC-KF03Scientific and Technological Planning Project of Guangzhou City () 2025B03J0032; 2023B03J1267
6 · The paper itself

Abstract

Rhabdoviruses exhibit a broad host range, yet the cellular receptors underlying their cross-species tropism remain poorly defined. Here, we identified tetraspanin CD9 as a conserved functional entry receptor for diverse rhabdoviruses across genera, including viral hemorrhagic septicemia virus (VHSV) (

Indexed as

Receptors, VirusRhabdoviridaeTetraspanin 29Virus InternalizationAnimalsHEK293 CellsHumansRhabdoviridae InfectionsZebrafishReceptors, VirusTetraspanin 29CD9nitazoxaniderhabdovirusesVHSVVSV

Identifiers

PMID41811454
PMCPMC12993960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.