Evidence map›Paper›PMID 41811449›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Viral mimicry may help explain immunogenic cell death.

Matthew S Levine, Jiexi Li, Lauren I R Ehrlich, Ronald A DePinho, Brent Iverson, Jonathan L Sessler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew S LevineDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712-1224.ORCID 0000-0002-2622-2678
Jiexi LiDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054.ORCID 0000-0003-1508-5732
Lauren I R EhrlichDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712-0159.ORCID 0000-0002-1697-1755
Ronald A DePinhoDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054.ORCID 0000-0002-5625-577X
Brent IversonDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712-1224.ORCID 0000-0001-7974-3605
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712-1224.ORCID 0000-0002-9576-1325

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
Super-Resolution OMX MicroscropeS10RR029552 · NCRR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ZAL, TOMASZ · 2011 to 2011
$1.0M
HHS | NIH (NIH) CA068682NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA068682NCRR NIH HHS S10 RR029552Welch Foundation (The Welch Foundation) F-0018
6 · The paper itself

Abstract

Viral mimicry may be an underappreciated contributor to chemotherapeutic potency in animal models and patients. This hypothesis is based on studies of a bis-Au(I)-NHC complex that was found to generate a strong

Indexed as

Colorectal NeoplasmsImmunogenic Cell DeathMolecular MimicryAnimalsChemokine CXCL10DEAD-box RNA HelicasesEndoplasmic Reticulum StressHumansInterferon-Induced Helicase, IFIH1MiceReactive Oxygen SpeciesUnfolded Protein ResponseChemokine CXCL10DEAD-box RNA HelicasesIfih1 protein, mouseInterferon-Induced Helicase, IFIH1Reactive Oxygen Speciescancerimmunogenic cell deathviral mimicry

Identifiers

PMID41811449
PMCPMC12993983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.