Evidence map›Paper›PMID 41811410›Full record

ArticleBulletin of experimental biology and medicine2025

Evaluation of Experimental Titanium Alloy Implants with Calcium Phosphate Coating and Antibacterial Components against Gram-Positive Pathogens: An Experimental Study.

A V Popkov, N A Kononovich, I V Shipitsyna, A L Shastov, D A Popkov, S I Tverdokhlebov, A I Kozelskaya, S I Goreninskii, K N Verzunova

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A V PopkovIlizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
N A KononovichIlizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia. n.a.kononovich@mail.ru.
I V ShipitsynaIlizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
A L ShastovIlizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
D A PopkovIlizarov National Medical Research Centre for Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Kurgan, Russia.
S I TverdokhlebovNational Research Tomsk Polytechnic University, Tomsk, Russia.
A I KozelskayaNational Research Tomsk Polytechnic University, Tomsk, Russia.
S I GoreninskiiNational Research Tomsk Polytechnic University, Tomsk, Russia.
K N VerzunovaNational Research Tomsk Polytechnic University, Tomsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibacterial properties of experimental titanium alloy implant samples (disks with a diameter of 10.0 ± 1 mm and thickness 1.0 mm) with a calcium-phosphate coating including an antibacterial component (vancomycin and cefazolin) against gram-positive pathogens (Staphylococcus aureus, S. epidermidis, Enterococcus faecalis) were studied in vitro using the disk diffusion method. The tested antibiotic concentrations were 2.5, 5.0, and 7.5 wt% in dry matter. Implants with vancomycin at all three concentrations exhibited a pronounced antibacterial effect against reference strains of S. aureus, S. epidermidis, and E. faecalis. Implants with cefazolin were effective only against S. aureus.

Indexed as

AlloysAnti-Bacterial AgentsCalcium PhosphatesCoated Materials, BiocompatibleTitaniumCefazolinEnterococcus faecalisMicrobial Sensitivity TestsStaphylococcus aureusStaphylococcus epidermidisVancomycinAlloysAnti-Bacterial Agentscalcium phosphateCalcium PhosphatesCefazolinCoated Materials, BiocompatibleTitaniumVancomycinimplant; bactericidal effect; gram-positive bacteria

Identifiers

PMID41811410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.