Evidence map›Paper›PMID 41811405›Full record

ArticleOdontology2026

Effects of desensitizing treatments on acid-etched dentin: debris precipitation, bond strength and tag formation.

Vitória Lacerda Santos, Alejandro Nicolás Tejada Medina, Antônia Patricia Oliveira Barros, Wilfredo Gustavo Escalante-Otárola, Cristiane de Melo Alencar, Milton Carlos Kuga

Abstract read
In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vitória Lacerda SantosDepartment of Restorative Dentistry, Araraquara Dental School, Sao Paulo State University-UNESP, Araraquara, SP, Brazil. vitoria.lacerda@unesp.br.ORCID http://orcid.org/0000-0002-0711-8816
Alejandro Nicolás Tejada MedinaDepartment of Restorative Dentistry, Araraquara Dental School, Sao Paulo State University-UNESP, Araraquara, SP, Brazil.
Antônia Patricia Oliveira BarrosDepartment of Restorative Dentistry, Araraquara Dental School, Sao Paulo State University-UNESP, Araraquara, SP, Brazil.
Wilfredo Gustavo Escalante-OtárolaSchool of Dentistry, Universidad Católica de Santa Maria - UCSM, Arequipa, Peru.
Cristiane de Melo AlencarSchool of Dentistry, University Center of the State of Pará-CESUPA, Belém, PA, Brazil.
Milton Carlos KugaDepartment of Restorative Dentistry, Araraquara Dental School, Sao Paulo State University-UNESP, Araraquara, SP, Brazil.

Funding

CNPQ 313550/2023-9
6 · The paper itself

Abstract

To evaluate the effects of formulations containing potassium nitrate, silicate, and calcium phosphate, subjected to an acid challenge, on debris precipitation, quantification of exposed dentinal tubules, bond strength, failure mode, and tag formation. One hundred and twenty bovine incisors were randomly allocated into four groups: Desensibilize NanoP, Desensibilize KF 2%, Regenerate NR-5, and a control group. Specimens were immersed daily for 5 min in orange juice (pH 3.80 ± 0.04) and then rinsed with distilled water. Forty teeth were analyzed by scanning electron microscopy to assess debris precipitation and tubular occlusion. Another forty were subjected to micro-shear bond strength testing, and the remaining forty were analyzed under optical microscopy for tag formation. Data were analyzed using the Kruskal-Wallis/Dunn test (debris precipitation) and ANOVA/Tukey test (open tubules, bond strength, and tag formation), with a significance level of α = 0.05. The Regenerate group showed significantly higher debris precipitation, fewer open dentinal tubules, greater bond strength, and a higher incidence of cohesive failures. Tag formation was similar across all groups. The Regenerate protocol demonstrated superior performance in debris precipitation, tubule occlusion, bond strength, and tag formation, particularly when used in combination with a universal adhesive.

Indexed as

Acid Etching, DentalDental BondingDentinDentin Desensitizing AgentsAnimalsCalcium PhosphatesCattleIn Vitro TechniquesMaterials TestingMicroscopy, Electron, ScanningNitratesPotassium CompoundsShear StrengthCalcium PhosphatesDentin Desensitizing AgentsNitratesPotassium Compoundspotassium nitrateDentin bonding agentsDentin desensitizing agentsDentin permeabilityDentin sensitivityTooth erosion

Identifiers

PMID41811405
PMCPMC13630804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.