Evidence map›Paper›PMID 41811404›Full record

ArticleOdontology2026

Transcriptomic response to compressive force simulating orthodontic tooth movement in cultured porcine epithelial cell rests of Malassez.

Yosuke Doi, Katsumitsu Shimada, Yuri Watanabe, Osamu Uehara, Koki Yoshida, Toru Kageyama, Yoshimi Kawahara, Yoshihiro Abiko, Satoshi Murakami

Abstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yosuke DoiHard Tissue Pathology Unit, Graduate School of Oral Medicine, Matsumoto Dental University, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan.ORCID http://orcid.org/0009-0008-2518-9926
Katsumitsu ShimadaDepartment of Clinical Pathophysiology, School of Dentistry, Matsumoto Dental University, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan. katsumitsu.shimada@mdu.ac.jp.ORCID http://orcid.org/0009-0002-9786-2581
Yuri WatanabeDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Matsumoto Dental University, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan.ORCID http://orcid.org/0009-0005-3323-289X
Osamu UeharaDivision of Disease Control and Molecular Epidemiology, Department of Oral Growth and Development, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.ORCID http://orcid.org/0000-0001-5602-4448
Koki YoshidaDivision of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.ORCID http://orcid.org/0000-0002-3792-9011
Toru KageyamaDepartment of Orthodontic Clinic, Matsumoto Dental University Hospital, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan.ORCID http://orcid.org/0000-0002-6381-1690
Yoshimi KawaharaDepartment of Orthodontics, School of Dentistry, Matsumoto Dental University, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan.ORCID http://orcid.org/0009-0009-7827-876X
Yoshihiro AbikoDivision of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.ORCID http://orcid.org/0000-0001-6358-8508
Satoshi MurakamiHard Tissue Pathology Unit, Graduate School of Oral Medicine, Matsumoto Dental University, 1780 Gobara Hirooka, Shiojiri, Nagano, 399-0781, Japan.ORCID http://orcid.org/0009-0005-7091-876X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical stress on the periodontal ligaments, such as orthodontic force, causes the failure of homeostasis-inducing inflammation leading to inflammatory root resorption and replacement resorption. Despite these developments during orthodontic treatment, little is known about its relationship to the epithelial cell rests of Malassez (ERM) located in the periodontal ligament. To address this gap, RNA sequencing was performed on non-compression and compression forced porcine ERM groups subjected to 4.0 g/cm

Indexed as

Compressive forceEpithelial cell rests of MalassezOrthodontic tooth movementPeriodontal ligament homeostasisPorcineRNA sequencing

Identifiers

PMID41811404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.