ArticleOrthodontics & craniofacial research2026
The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth.
Article in Orthodontics & craniofacial research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe mid-palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte-derived osteogenesis to maxillary bone formation and the influence of dietary loading on this process.
methodsTwo chondrocyte-lineage tracing mouse models were utilised: Aggrecan-Cre
resultsSoft diet feeding significantly reduced maxillary arch width, bone volume and bone mineral density in the mid-palatal region. Although chondrocyte proliferation was comparable between groups, differentiation was notably impaired. Lineage tracing demonstrated that both Acan
conclusionsAcan
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