Evidence map›Paper›PMID 41810963›Full record

ArticleMicrobiology spectrum2026

Fatty acid transporter protein isoform 2 (FATP2) inhibitor lipofermata inhibits Zika virus replication and blocks fatty acid uptake in SH-SY5Y neuroblastoma cell line.

Songkran Thongon, Chompunuch Boonarkart, Thanyaporn Sirihongthong, Kunlakanya Jitobaom, Kessiri Kongmanas, Prasert Auewarakul

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Songkran ThongonGraduate Program in Molecular Medicine, Faculty of Science, Mahidol University, Bangkok, Thailand.
Chompunuch BoonarkartDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Thanyaporn SirihongthongDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kunlakanya JitobaomDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kessiri KongmanasDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Prasert AuewarakulDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-4745-4291

Funding

Faculty of Medicine Siriraj Hospital, Mahidol UniversityNational Research Council of Thailand N42A670585Research Excellence Development: RED program, Faculty of Medicine Siriraj Hospital, Mahidol UniversityThailand Science Research and Innovation IRN60W0002The National Science and Technology Development Agency (NSTDA), the Chair Professor Program P-20-52262
6 · The paper itself

Abstract

Zika virus (ZIKV) infection in adults is typically mild and self-limiting, but infection during pregnancy can cause fetal and neonatal microcephaly. No approved drugs or vaccines currently exist. ZIKV hijacks host lipid homeostasis to facilitate replication, and inhibitors of fatty acid synthesis decrease its production. However, cells obtain lipids from both

Indexed as

Antiviral AgentsFatty AcidsFatty Acid Transport ProteinsVirus ReplicationZika VirusApoptosisCell Line, TumorHumansNeuroblastomaNeuronsZika Virus InfectionAntiviral AgentsFatty AcidsFatty Acid Transport ProteinsFATP2fatty acid uptakelipofermataneuroblastomavirus-lipid interactionZika

Identifiers

PMID41810963
PMCPMC13055220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.