ArticlemSphere2026
Transcriptomic analysis of tigecycline-induced colistin collateral sensitivity in carbapenem-resistant
Youtao Liang, Jiming Wu, Jisheng Zhang, Chunli Wei, Jianmin Wang, Wenzhang Long, Xueke Jiang, Yang Yang, Mingjing Liao, Xuemei Gou and 1 more
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In one paragraphArticle in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Youtao Liang *Department of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.ORCID 0009-0008-8235-721X Jiming Wu *Department of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jisheng ZhangDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Chunli WeiDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Jianmin WangDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Wenzhang LongDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xueke JiangDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Yang YangDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Mingjing LiaoDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xuemei GouDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-1951-0978 Xiaoli ZhangDepartment of Microbiology, the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-9385-8107 Funding
Chongqing Medical University Affiliated Yongchuan Hospital Postgraduate Innovation Fund YJSCX202404Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission CSTB2024NSCQ-MSX0253Noncommunicable Chronic Diseases-National Science and Technology Najor Proiect 2024ZD0533106/2024ZD0533100Yongchuan Natural Science Foundation 2025yc-cxfz10114
6 · The paper itselfAbstract
Utilizing treatment strategies based on collateral sensitivity (CS) represents a promising approach to suppressing antibiotic resistance. Although the mechanism of CS between numerous drugs has been researched, the mechanism of CS between tigecycline and colistin remains unclear. Therefore, the purpose of our research is to investigate the possible mechanism by which tigecycline affects colistin CS in the
Indexed as
Anti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeColistinDrug Resistance, BacterialEnterobacter cloacaeGene Expression ProfilingTigecyclineBacterial ProteinsBiofilmsCarbapenemsMicrobial Sensitivity TestsTranscriptomeAnti-Bacterial AgentsBacterial ProteinsCarbapenemsColistinTigecyclinecolistincollateral sensitivityEnterobacter cloacae complextigecyclinetranscriptomics
Identifiers
PMID41810944
PMCPMC13037404
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