Evidence map›Paper›PMID 41810920›Full record

ArticleBehavioural neurology2026

The Burden of Epilepsy in Thailand: Estimating Societal Costs and Quality of Life.

Prapassara Sirikarn, Surachai Phimha, Luxzup Wattanasukchai, Sineenard Mungmanitmongkol, Somsak Tiamkao

Abstract read
In one paragraph

Article in Behavioural neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Prapassara SirikarnDepartment of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0001-5887-6716
Surachai PhimhaDepartment of Public Health Administration, Health Promotion, and Nutrition, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0003-2248-546X
Luxzup WattanasukchaiClinical Epidemiology Unit, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0001-5174-4788
Sineenard MungmanitmongkolIntegrated Epilepsy Research Group, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0009-0007-1000-432X
Somsak TiamkaoIntegrated Epilepsy Research Group, Khon Kaen University, Khon Kaen, Thailand, kku.ac.th.ORCID https://orcid.org/0000-0001-5178-478X

Funding

Khon Kaen University
6 · The paper itself

Abstract

backgroundEpilepsy imposes both economic and quality-of-life (QOL) burdens. Therefore, this study is aimed at evaluating the costs of illness and QOL in patients with epilepsy (PWE) and their caregivers and to examine the differences in costs and QOL across patient characteristics.

methodsThis prevalence-based cost-of-illness study was conducted from a societal perspective. Data were collected from patients who attended the Epilepsy Clinic at Srinagarind Hospital, Khon Kaen University, between April and August 2023. QOLs were assessed using the Quality of Life in Epilepsy Inventory-31 (QOLIE-31) for PWE and the EuroQoL-5D-5L (EQ-5D-5L) for caregivers. A generalized linear model was used to assess the differences in costs and QOL across patient and caregiver characteristics.

resultsA total of 214 subjects were enrolled in this study, comprising 129 PWE and 85 caregivers. The mean total cost of illness per outpatient visit was 452.27 PPP-USD, with 58.0% attributed to direct medical costs, 24.4% to direct nonmedical costs, and 17.6% to indirect costs. Direct medical costs differed significantly based on employment status (p value = 0.031) and seizure control (p value = 0.018). Direct nonmedical costs showed differences by residential distance (p value < 0.001). Indirect costs also showed differences by age (p value = 0.019) and residential distance (p value = 0.002). The lifetime productivity loss from unemployment reached 14638.37 PPP-USD per patient. The mean overall QOLIE-31 score was 74.04 points, and the mean EQ-5D-5L index was 0.90. There were differences in QOL based on age and seizure control in PWE, as well as age and unemployment status in caregivers.

conclusionDirect medical costs were the largest component of total costs. Cost differences were found across age, employment status, residential distance, and seizure control. QOL varied by age and seizure control in PWE and by age and unemployment status in caregivers.

Indexed as

Cost of IllnessEpilepsyHealth Care CostsQuality of LifeAdolescentAdultAgedCaregiversFemaleHumansMaleMiddle AgedThailandYoung Adultcarerdirect costseconomicindirect costsquality of lifeseizure

Identifiers

PMID41810920
PMCPMC13580846

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.