Evidence map›Paper›PMID 41810826›Full record

ArticleBiochemistry2026

Darius Chernitsky-Hamd, Rajat Roy, Jonas Schemm, Aubrey Schall, Mera Petros, Andreas Willems, Paul D Roepe

Abstract read
In one paragraph

Article in Biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darius Chernitsky-HamdDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.
Rajat RoyDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.
Jonas SchemmDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.
Aubrey SchallDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.ORCID 0009-0008-0908-7997
Mera PetrosDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.
Andreas WillemsDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.
Paul D RoepeDept. of Chemistry and Dept. of Biochemistry and Cellular and Molecular Biology, Georgetown University, 37th and O Streets NW, Washington, D.C. 20057, United States.ORCID 0000-0002-7079-3793

Funding

The Function of Antimalarial Drug Resistance ProteinsR01AI056312 · NIAID · GEORGETOWN UNIVERSITY · PI PAUL D. ROEPE · 2003 to 2026
$7.5M
NIAID NIH HHS R01 AI056312
6 · The paper itself

Abstract

The recently elucidated atomic resolution cryo-EM structure of the 7G8 isoform of

Indexed as

ChloroquineMembrane Transport ProteinsPlasmodium falciparumProtozoan ProteinsAntimalarialsDrug ResistanceMolecular Dynamics SimulationMutagenesis, Site-DirectedOxidation-ReductionAntimalarialsChloroquineMembrane Transport ProteinsPfCRT protein, Plasmodium falciparumProtozoan Proteins

Identifiers

PMID41810826
PMCPMC13063427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.