Evidence map›Paper›PMID 41810683›Full record

ArticleMemorias do Instituto Oswaldo Cruz2026

Miracidia as main source for autofluorescence of Schistosoma mansoni eggs

Danielle Segóvia Chrysóstomo de Almeida Pereira, Laila Oliveira Vaz Oliveira Oliveira, Felipe Tonon Firmino, Thomas Hanscheid, Rock Pulak, Malcolm Jones, Silvio Dolabella, Deborah Negrão-Corrêa, Carlos Graeff-Teixeira

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Article in Memorias do Instituto Oswaldo Cruz, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danielle Segóvia Chrysóstomo de Almeida PereiraUniversidade Federal do Espírito Santo, Núcleo de Doenças Infecciosas, Helmintologia, Vitória, ES, Brasil.
Laila Oliveira Vaz Oliveira OliveiraUniversidade Federal do Espírito Santo, Núcleo de Doenças Infecciosas, Helmintologia, Vitória, ES, Brasil.
Felipe Tonon FirminoUniversidade Federal do Espírito Santo, Núcleo de Doenças Infecciosas, Helmintologia, Vitória, ES, Brasil.
Thomas HanscheidUniversidade de Lisboa, Escola de Medicina, Lisboa, Portugal.
Rock PulakUnion Biometric, Holliston, MA, United States of America.
Malcolm JonesUniversity of Queensland, School of Veterinary Sciences, Gatton, Australia.
Silvio DolabellaUniversidade Federal de Sergipe, Centro de Ciências Biológicas e da Saúde, Entomologia e Parasitologia Tropical, Aracaju, SE, Brasil.
Deborah Negrão-CorrêaUniversidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Carlos Graeff-TeixeiraUniversidade Federal do Espírito Santo, Núcleo de Doenças Infecciosas, Helmintologia, Vitória, ES, Brasil.ORCID 0000-0003-2725-0061

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEgg detection still has a role in schistosomiasis control, as a screening strategy or to provide a reference standard for the assessment of the accuracy of other diagnostic tools. The Helmintex method is highly sensitive but laborious, and several improvements of it, including automated egg detection, are currently under development.

objectiveWe conducted a preliminary evaluation of Schistosoma mansoni eggs' autofluorescence as a distinctive marker amid very complex fecal sediments.

methodsEggs from mouse livers and human feces were examined under a fluorescence microscope.

findingsMore intense green fluorescence (greater for miracidia than for eggshell) was consistently detected using a B-2A filter (FITC, 420-495 nm). MAIN

conclusionsThese findings may help to improve diagnostic methods, especially with automated egg detection systems. Besides access to safe water and adequate sanitation, as well as health education and the treatment of infected individuals, laboratory diagnosis is a key measure that can help eliminate schistosomiasis as a public health problem.

Indexed as

FecesLiverSchistosoma mansoniSchistosomiasis mansoniAnimalsFemaleFluorescenceHumansMiceMicroscopy, FluorescenceOvumParasite Egg Count

Identifiers

PMID41810683
PMCPMC12971022

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.