Evidence map›Paper›PMID 41810532›Full record

ArticleHead & neck2026

Toward a Typology of Patients With Head and Neck Cancer: Biopsychosocial Profiles Predicting Longitudinal Quality of Life.

Haley Deamond, Cyril Devault-Tousignant, Jacob Lang, Christopher Lo, Jennifer Silver, Nader Sadeghi, Zeev Rosberger, Saul Frenkiel, Michael Hier, Anthony Zeitouni and 9 more

Abstract read
In one paragraph

Article in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Haley DeamondMcGill University, Montreal, Quebec, Canada.ORCID 0000-0002-2900-246X
Cyril Devault-TousignantMcGill University, Montreal, Quebec, Canada.
Jacob LangMcGill University, Montreal, Quebec, Canada.ORCID 0000-0003-3749-7199
Christopher LoDepartment of Psychology, Tropical Futures Institute, James Cook University, Singapore, Singapore.
Jennifer SilverMcGill University, Montreal, Quebec, Canada.
Nader SadeghiMcGill University, Montreal, Quebec, Canada.ORCID 0000-0002-3218-2668
Zeev RosbergerMcGill University, Montreal, Quebec, Canada.
Saul FrenkielMcGill University, Montreal, Quebec, Canada.
Michael HierMcGill University, Montreal, Quebec, Canada.
Anthony ZeitouniMcGill University, Montreal, Quebec, Canada.
Karen KostMcGill University, Montreal, Quebec, Canada.
Alex MlynarekMcGill University, Montreal, Quebec, Canada.
Keith RichardsonMcGill University, Montreal, Quebec, Canada.
Gabrielle ChartierJewish General Hospital, Montreal, Quebec, Canada.
Marco MascarellaMcGill University, Montreal, Quebec, Canada.ORCID 0000-0002-8880-805X
Khalil SultanemMcGill University, Montreal, Quebec, Canada.
Georges ShenoudaMcGill University, Montreal, Quebec, Canada.
Fabio CuryMcGill University, Montreal, Quebec, Canada.
Melissa HenryMcGill University, Montreal, Quebec, Canada.

Funding

Fonds de Recherche du Québec-Santé 24910
6 · The paper itself

Abstract

backgroundQuality of life (QoL) in head and neck cancer (HNC) is influenced by complex biopsychosocial factors, yet few longitudinal studies have examined these relationships immediately post-treatment.

methodsIn this prospective study, 232 patients newly diagnosed with primary HNC completed psychometric assessments, clinical interviews, and medical chart reviews at baseline, 3, 6, and 12 months. QoL was measured using the Functional Assessment of Cancer Therapy-HNC module. A two-step cluster analysis identified distinct biopsychosocial subgroups, and mixed ANOVA tested QoL trajectories across time.

resultsThree clusters emerged: (1) early-stage disease with low treatment intensity; (2) high psychological burden and (3) advanced disease with high treatment intensity. These were associated with highest QoL, persistently lowest QoL (p < 0.001), and intermediate QoL that improved over time respectively.

conclusionsPsychological distress exerted a stronger influence on QoL than medical burden. Early identification and intervention for psychosocial risk factors may optimize recovery in HNC patients.

Indexed as

Head and Neck NeoplasmsQuality of LifeAdultAgedCluster AnalysisFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesPsychometricsStress, PsychologicalSurveys and Questionnairescluster analysishead and neck neoplasmsotolaryngologyquality of liferisk factors

Identifiers

PMID41810532
PMCPMC13332574

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.