ArticleFrontiers in veterinary science2026
OncoCan: a liquid biopsy assay for cell-free DNA quantification in canine plasma to support cancer prognosis.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
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9 authors.
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Abstract
Early cancer detection remains a major challenge in veterinary medicine. Cell-free DNA (cfDNA), released into the bloodstream through apoptosis, necrosis, or circulating tumor cells, can be quantified non-invasively via liquid biopsy and is already established in human oncology. In this study, we evaluated OncoCan, a targeted plasma cfDNA assay, by analyzing samples from 83 dogs with various neoplasms and 47 healthy controls to assess diagnostic and prognostic utility. Wilcoxon rank-sum testing revealed significantly higher cfDNA concentrations in neoplastic versus healthy samples (
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