Evidence map›Paper›PMID 41810217›Full record

Trial reportBioMed research international2026

Effects of Ubiquinol on Oxidized Low-Density Lipoprotein in Prediabetic Patients: A Randomized, Double-Blinded, Placebo-Controlled Study.

Romun Leaovitavat, Pasita Palakornkitti, Paphitchaya Thetsana, Patana Teng-Umnuay

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Romun LeaovitavatAnti-Aging and Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand, dpu.ac.th.ORCID https://orcid.org/0009-0001-0044-6323
Pasita PalakornkittiAnti-Aging and Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand, dpu.ac.th.
Paphitchaya ThetsanaCollege of Health and Wellness, Dhurakij Pundit University, Bangkok, Thailand, dpu.ac.th.
Patana Teng-UmnuayAnti-Aging and Regenerative Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand, dpu.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objectives: Oxidized low-density lipoprotein (oxLDL) has emerged as a promising biomarker of oxidative burden and cardiovascular risk. This study is aimed at evaluating the effect of ubiquinol supplementation, a potent lipophilic antioxidant, on oxLDL levels in prediabetic patients. Methods: This was a prospective, randomized, double-blinded, placebo-controlled pilot study of 20 adults with impaired fasting plasma glucose (FPG). Participants were randomized to receive either ubiquinol (100 mg/day) or placebo for 12 weeks. Plasma oxLDL levels were measured at baseline and Week 12. Results: After 12 weeks, the ubiquinol group demonstrated a significant within-group reduction in plasma oxLDL compared with baseline ( Conclusions: Daily ubiquinol (100 mg/day) for 12 weeks was associated with a significant within-group decrease in plasma oxLDL among prediabetic participants; however, the between-group difference versus placebo was not significant. Trial Registration: Thai Clinical Trials Registry: TCTR20250512008.

Indexed as

Lipoproteins, LDLPrediabetic StateUbiquinoneAdultAntioxidantsBlood GlucoseDouble-Blind MethodFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesAntioxidantsBlood GlucoseLipoproteins, LDLoxidized low density lipoproteinubiquinolUbiquinone

Identifiers

PMID41810217
PMCPMC12968332

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.