ArticleTranslational pediatrics2026
Congenital mesoblastic nephroma: a single-center retrospective study.
Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Congenital mesoblastic nephroma (CMN) is a rare renal tumor predominantly occurring in neonates and young infants, and standardized treatment guidelines remain lacking. This study aimed to summarize the clinical features, therapeutic strategies, and outcomes of CMN patients from a single institution to inform clinical practice. Methods: We retrospectively reviewed the medical records of nine children with pathologically and molecularly confirmed CMN treated at Children's Hospital of Nanjing Medical University between 2015 and 2024. Demographic characteristics, clinical presentation, imaging findings, histological subtypes, gene fusions, treatment approaches, and follow-up data were analyzed. Results: The median age at diagnosis was 2.5 months (range: newborn to 93 months), with a male-to-female ratio of 2:1. Most patients (90%) presented with an abdominal mass detected prenatally or incidentally. The tumor originated from the right kidney in seven cases and the left in two. Ultrasound and computed tomography (CT) commonly revealed mixed cystic-solid masses, with heterogeneous enhancement on contrast imaging. Pathological subtypes included cellular (n=5), classic (n=2), and mixed (n=2). Of seven patients undergoing fluorescence in situ hybridization (FISH), three were positive for the Conclusions: This small single-center case series describes the clinical and molecular heterogeneity of CMN. While most patients experienced favorable outcomes following surgery, relapsed cases highlight the challenges associated with molecularly atypical disease. These observations are descriptive in nature and underscore the need for larger collaborative studies to better define prognostic factors and optimal management strategies in CMN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.