Evidence map›Paper›PMID 41810120›Full record

ArticleVeterinary and animal science2026

Effect of

Matheus Camargos de Britto Rosa, Maria Eduarda de Souza Teixeira Campos, Adriana Silva Albuquerque, Mirian Silvia Braz, Rilary de Oliveira Mapele, Maria Carolina Garcia de Oliveira, Hugo Shisei Toma, Patrícia Ferreira Ponciano Ferraz, Rodrigo Norberto Pereira, Djeison Lutier Raymundo

Abstract read
In one paragraph

Article in Veterinary and animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matheus Camargos de Britto RosaCentro Universitário de Lavras, UNILAVRAS, Caixa Postal 3141, CEP 37200-000, Lavras, MG, Brasil.
Maria Eduarda de Souza Teixeira CamposDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.
Adriana Silva AlbuquerqueUnidade de Estabilização de Fauna Marinha - Laboratório de Zoologia, Caixa postal 1873, CEP 88790-000, Laguna, SC, Brasil.
Mirian Silvia BrazDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.
Rilary de Oliveira MapeleDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.
Maria Carolina Garcia de OliveiraCentro Universitário de Lavras, UNILAVRAS, Caixa Postal 3141, CEP 37200-000, Lavras, MG, Brasil.
Hugo Shisei TomaUniversidade Federal de Uberlândia (UFU), Caixa Postal 593, CEP 38400-902, Uberlândia, MG, Brasil.
Patrícia Ferreira Ponciano FerrazDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.
Rodrigo Norberto PereiraDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.
Djeison Lutier RaymundoDepartamento de Medicina Veterinária, Universidade Federal de Lavras, UFLA, Campus Universitário, Caixa Postal 3037, CEP 37202-203, Lavras, MG, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin wounds in horses, particularly in the distal extremities, often heal slowly due to mechanical stress, compromised perfusion, and excessive fibroplasia. This study evaluated the effects of topical Croton lechleri (CL) cream, alone or in combination with nitroglycerin, on the healing of skin wounds in the metatarsal region of horses. Six mares received six standardized wounds in each region and were treated with: saline solution, nitroglycerin (0.1 or 1 mg/mL), CL (1 or 10 µg/mL), or CL + nitroglycerin (10 µg/mL + 1 mg/mL). Wound contraction, histology, and bacterial culture were evaluated. Wounds treated with CL demonstrated increased collagen deposition and reduced angiogenesis over time. Nitroglycerin reduced vessel count over time in metatarsal wounds but did not significantly alter contraction. In conclusion, Croton lechleri appears to aid in tissue repair by modulating collagen deposition, angiogenesis, and inflammation.

Indexed as

Croton lechleriEquinesHealingLush Granulation fabricNitroglycerinWounds

Identifiers

PMID41810120
PMCPMC12969322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.